The End of Death as We Know It?

Longevity researchers aren’t just on the cusp of extending the number of years people live. They’re also discovering ways to prevent and treat the physical ailments and neurodegenerative diseases that often come with age. In this collection of features, essays, and op-eds, Freethink maps the frontier — from lab breakthroughs to clinical trials and the startups scaling them — separating hype from evidence, while also exploring some of the philosophical and ethical questions surrounding the longevity movement. We hope you enjoy.

Illustration of two human profiles facing opposite directions, overlaid with a stylized DNA double helix and circular patterns, on a gradient background.
Vartika Sharma
Editor's Note
The promise of longevity: A future with more time — and more meaning
An introduction to Freethink’s Longevity Issue: features, essays, and op-eds on the science, ethics, and promise of longer, healthier lives.

“The first longevity medicines could be approved in time for most people alive today — maybe even in the next five years, if we get serious about the science.”

Andrew Steele
Field Notes
Longevity progress is real. So are the scams.
Longevity is in a paradoxical place at the moment, with anti-aging influencers misrepresenting real progress in order to make money.
Who wants to live forever? Not me.
Most Americans remain wary of immortality, and research helps explain the mix of ethics, faith, and fear behind that resistance.
Aubrey de Grey: “We need a COVID-scale war on aging.”
Biomedical gerontologist Aubrey de Grey discusses the burgeoning longevity movement and barriers to its progress.
Why tomorrow’s longevity treatments could be divided by sex
Why women consistently outlive men is a mystery — and it may influence the future of longevity medicine.

“Dogs are a great model of human aging. If something works in a dog … it’s pretty compelling evidence that it might also work in a human.”

Celine Halioua
Frontiers
Retro Biosciences wants to add 10 healthy years to your life
Backed by $180 million in funding from OpenAI’s Sam Altman, Joe Betts-LaCroix’s Retro Biosciences is racing to extend the human healthspan.
How a dog’s life could extend yours
Studying animals — from long-lived clams to everyday dogs — is helping scientists understand aging and design therapies to slow decline.
My time among the immortality tribe
Field notes from Vitalist Bay, an 8-week longevity zone in Berkeley where CEOs, scientists, and activists united to fight aging.
How cryopreservation could end death as we know it
The technology could one day allow people with terminal illnesses to go into “hibernation” until a cure is found.
The longevity movement is growing — but it needs to go global
Progress in longevity is real, but experts say the field needs government funding, policy reform, and public buy-in to reach its potential.
Living longer — and healthier — starts with boosting your brain
Science is beginning to unravel the reasons behind age-related cognitive decline — and what we can do about it.

“I’m just brimming with optimism because I know we can do this. We can flip the elderly from being the ‘illderly’ to the ‘wellderly.’”

Eric Topol
Interfaces
Forget just living longer. Eric Topol wants to help Americans live better, too.
In “Super Agers,” the writer and medical researcher maps a path to extending healthspan with AI, targeted drugs, and lifestyle changes.
Experts weigh in on popular “anti-aging” treatments: real or scam?
Experts cut through longevity hype, debunking supplements, IV drips, and cold plunges while pointing to what actually works.
AI deadbots can keep “you” around after death — what does that mean for the living?
We can now use AI to create versions of real people that can live on long after their bodies die. But should we?
Groundhog Day and other eternal nightmares: Five philosophical takes on living forever
From eternal recurrence to techno-dualism, five philosophical visions of immortality — and why most paths to forever end badly.
Immortality isn’t progress. It’s paralysis.
The pursuit of immortality ignores how death powers life’s natural cycles, from cellular turnover to ecological renewal and adaptation.
A close-up of a hand divided down the center, with one side appearing wrinkled and spotted, and the other side smooth and youthful.
If aging is a disease, how close are we to curing it?
We’ve already doubled human life expectancy over the last 200 years. Could we do it again?