Harnessing Psychedelics

Breakthroughs in psychedelics are leading to a paradigm shift in well being. How can we accelerate progress and what will our relationship with drugs look like as this movement goes mainstream? 
psychedelic research center
Mount Sinai is opening a psychedelic research center
A pacesetting institution, the Icahn School of Medicine at Mount Sinai is opening a psychedelic research center focusing on MDMA and trauma.
medical cannabis
Medical cannabis explained 
Medical cannabis is everywhere. We’re answering your basic questions and unpacking the promises and pitfalls, based on the latest research.
drug use
Series | Dope Science
The Drug Users Bible: A guide to safe drug use5:06
Over a 10 year period, Dominic Milton Trott self-administered 157 psychoactive drugs and documented his experiences on each one. He then created the book, The Drug Users Bible, to inform curious minds about safe drug use.
See Another Challenge

We now have the tools to control evolution. How will DIY biology improve our brains and our bodies, and what impacts will this have on society?

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Psychedelic Mushrooms
Scientists want to study your at-home psychedelic mushroom experiences
Scientists are looking for people planning to trip on psychedelic mushrooms for a new study focused on people’s “real-world” experiences with psilocybin.
the war on drugs
Series | Dope Science
Are social media giants censoring life saving drug research?5:30
The first casualty of war is truth, and that applies to the war on drugs. Some are fighting back with harm reduction and drug education, yet they’re facing opposition from an unexpected source.
special K drug ketamine
Ketamine explained: Understanding the special k drug 
Ketamine, known recreationally as the “Special K” drug, is a trance-inducing anesthetic that researchers believe has more powerful uses off the dance floor.
microdosing psychedelics
Series | Dope Science
Microdosing psychedelics5:56
Microdosing is the no-flowers-in-your-hair practice of regularly taking minimal amounts of hallucinogenic substances. Although it’s currently illegal, millions of dollars are being poured into further research.
tbg for stress
A small dose of an ibogaine-like drug cures stress in mice
A novel drug designed like ibogaine but without the ibogaine trip or toxicity has corrected the effects of stress in mice.
Fighting Depression
Series | Dope Science

I use ketamine for depression – here’s how it works

Ketamine’s reputation is moving away from “party drug” and into one of the newest and most effective forms of depression treatment.

ketamine for depression
Series | Dope Science

I use ketamine for depression – here’s how it works

ketamine for depression
Breakthrough Treatments
Natural Treatment for Autism
Series | Dope Science
Cannabis as a natural treatment for autism7:07
When typical medications simply aren’t doing enough to manage their children’s symptoms, mothers like Jenni Mai are turning to medical marijuana. But with current regulations, parents are having to become pharmacists for their own families, and some are even moving across the country so they can legally access cannabis.
microdosing lsd
Microdosing LSD may provide pain relief
Since the 1960s, LSD has been seen as a potential painkiller. Now, new research suggests microdosing LSD may indeed provide relief.
PTSD Treatment
MDMA has long-lasting benefits as a PTSD treatment
The benefits of MDMA therapy as a PTSD treatment appear to last for at least a year, according to a newly published paper.
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ergot alkaloids
Morning glories may be a source of new psychedelics and medicines
cannabis cooking
Traditional Thai cannabis cooking is back on the menu
Should psychedelics be patented
Frontline healthcare workers are going to receive psilocybin therapy 
Psilocybin treatment
Psilocybin treatment relieves depression in largest trial yet 
Johns Hopkins receives the first NIH grant for clinical psychedelic research in half a century
dendritic spines
Yale study: magic mushrooms may grow connections between brain cells
Is DMT the best new treatment for depression?7:08
tbg for stress
A small dose of an ibogaine-like drug cures stress in mice
ketamine infusion
Ketamine infusion: What it's like and how it works