Field: Medicine

A mouthwash solution containing ferumoxytol and a dye could treat, prevent, and diagnose tooth decay, according to UPenn researchers.

A microdevice that injects up to 20 drugs into gliomas at once could help doctors quickly identify the best treatment for cancer patients.

Approved over a decade ago, transcranial magnetic stimulation (TMS) could be effective if the treatment was tailored to individual brains.

A drug approved to treat multiple sclerosis reduced neuroinflammation and improved memory in mouse models of Alzheimer’s.

New trials will test the ability of GLP-1 agonists, a popular class of weight-loss drugs, to help people beat addictions to drugs and alcohol.

Honeypot ant honey may help develop our arsenal of effective antibacterial and antifungal treatments, which are increasingly vital.

A handful of people have already been functionally cured of HIV — and new, universal cures are just on the horizon.

A new obesity treatment developed at UMass triggered weight loss in mice even as they continued to eat a diet high in fat and sugar.

Transplants of lab-grown dopamine neurons reduced the amount of time people experienced Parkinson’s symptoms in a small trial.

An artificial kidney prototype just aced a pig trial, bringing it closer to human trials — and a step closer to ending the need for dialysis.

Placental cells known to home in on and repair damaged heart cells in mice have been discovered in humans, too.

Mitochondria are crucial for memory preservation and are emerging as key players in the fight against Alzheimer's.

Genetically engineered bacteria could be used to detect a range of different diseases, particularly infections and cancers.

Novo Nordisk’s popular weight-loss drug semaglutide (Wegovy) improved heart failure symptoms in a trial of more than 500 people.

New obesity treatments, including GLP-1 agonists and gene therapies, could make it easier for people to lose weight and keep it off.

A new gene therapy for the rare liver disorder Crigler-Najjar syndrome was highly effective in a small trial.

An in-development treatment for alcoholism dramatically reduced consumption in monkeys that previously drank heavily.

Chemists have shown how to manufacture ibuprofen and acetaminophen using a waste product from the forestry and paper industries.

The weight-loss drug semaglutide reduced patients’ risk of heart attacks, strokes, or death from heart disease by 20% in a large trial.

Researchers discovered that the mutated gene responsible for fragile X syndrome is active in most people with the disorder, not silenced.

Researchers found brain wave signatures that could help determine when patients are transitioning into a deep state of unconsciousness.

City of Hope researchers are trialing a targeted therapy shown to kill more than 70 types of cancer in preclinical tests.

Microglia perform many functions in the brain, and their role in seizures is unclear — a new study in mice aims to find out more.

A topical gene therapy designed to heal the wounds of people with “butterfly skin disease” has now been used to reverse blindness.

The FDA has approved nirsevimab, an RSV shot that protects babies against the leading cause of infant hospitalizations in the US.

Scientists reviewed 40 years of clinical studies that assessed the effects of NA-targeting drugs, such as certain ADHD drugs, on Alzheimer’s.

Radiopharmaceuticals allow doctors to directly target patients' cancer cells and avoid healthy tissue typically damaged by radiation therapy.

Researchers studied different types of mosquito repellents and their efficacy for over a decade. Here's what they found.

Islet transplantation, a procedure shown to functionally cure some people with hard-to-control brittle diabetes, has been approved in the US.

A drug that causes animals to grow new teeth could one day allow us to regenerate teeth lost to injury, disease, or old age.

Stanford University researchers have identified a new, hard-to-treat type of depression characterized by problems with cognition.

AI-driven drug development has led to the launch of phase 2 trials of a drug to treat idiopathic pulmonary fibrosis (IPF).

A new study has unlocked a “backdoor” into the inner ear that could make administering gene therapies to restore hearing less risky.

Low-calorie, intermittent-fasting, and ketogenic diets all can lower the amount of blood glucose available to fuel cancer cells.

Anti-inflammatory drugs could potentially prevent herpes encephalitis from causing permanent brain damage.

New research shows that nasal drops of neuropeptide Y triggers extinction of fear memories in an animal model of PTSD.

A stem cell-based treatment for epilepsy slashed the number of seizures experienced by two trial participants by 95%.

New synthetic insulin harvested from lettuce plants can be made cheaply, taken orally, and transported at room temperature.

Japanese researchers have discovered that the cancer drug sunitinib can prevent the formation of brain aneurysms in mice.

SpaceX has successfully deployed a “space factory” developed by startup Varda Space Industries to manufacture drugs in microgravity.

The diabetes drug metformin cut COVID-19 patients’ risk of later developing long COVID by 41% in a small study.

Israeli researchers have developed a new form of CAR-T therapy effective against multiple myeloma, a plasma cell cancer.

Henry Ford Health researchers are using temporary tattoo ink to help radiation therapy patients for whom permanent tattoos may not be an option.

A new NASH treatment, efruxifermin, significantly reduced liver fat when combined with a GLP-1 drug in a small trial.

Osimertinib, an FDA-approved lung cancer drug, slashes the risk of death for certain patients by 51%, according to new trial results.

Researchers at Johns Hopkins have found that genes associated with schizophrenia risk may impact the placenta, not just the brain.

Gain-of-function experiments in the lab can help researchers get ahead of viruses naturally gaining the ability to infect people in the wild.

Even though pain is universal and we know it happens in the brain, we've never before had a way to objectively measure its intensity.

The first treatments proven to slow cognitive decline in Alzheimer’s are helping settle a decades-long debate about how the disease starts.

To improve leukemia treatment, Australian researchers have created a bispecific antibody that connects chemo drugs to cancer cells.

Techniques borrowed from astrophysics are helping to advance personalized cancer treatments beyond what genetics can tell us.

This protein may help bats survive viral infections and could be the springboard for new anti-inflammatory drugs.

Researchers have found ibogaine-inspired compounds effective in treating depression and addiction in mouse models.

A surgical team has performed a surgery that alleviated a dangerous brain condition before it was too late.

A new pancreatic cancer vaccine based on mRNA tech was shown to be safe and capable of triggering an immune response in a small trial.

New research links the gut microbiome, an ecosystem of viruses, bacteria, and fungi, to the development of anorexia nervosa.

A new study suggests we may be able to convert dormant eye cells into photoreceptors to reverse retinal degeneration.

In a small study, Northwestern researchers were able to get chemo drugs into the brains of glioblastoma patients with implanted ultrasound devices.

A new AI tool can find the most stable mRNA sequence for a vaccine, leading to more effective shots that are less prone to degradation.

The FDA has approved the world’s first vaccine for RSV, a potentially deadly viral infection that has long eluded vaccination.

The FDA approval of the first fecal transplant pill could kick off an era in which we target the gut microbiome to treat many other diseases.

Researchers have measured gamma waves, a sign of brain activity, in patients who were dying.

Eli Lilly’s new Alzheimer’s drug, donanemab, slowed cognitive decline by 35% in a phase 3 trial, but two people died from side effects.

A Harvard study found that a new gene therapy that reprograms cells to their younger state can reverse NAION-caused vision loss in primates.

A new brain cancer treatment not only cured 100% of mice that received it, but also trained their immune systems to fight future cancers.

Ghana and Nigeria have become the first two nations to approve Oxford’s vaccine against malaria.

A new drug delivery system for pancreatic tumors could dramatically decrease medication dosages, helping minimize unpleasant side effects.

The famous placebo effect has a long, rich history — it certainly had an outsized role in the medicine of centuries past.

Scientists are starting to agree that the "holy grail" solution for Alzheimer's is more likely to be a drug cocktail than a single treatment.

MindMed and University Hospital Basel have announced top line results for their phase 2 trial.

Ants were just as accurate as cancer-sniffing dogs. Better yet, they could be trained in minutes rather than months.

In a study of CPR patients across the US and UK, researchers found new evidence about near-death experiences.

Tech platform Hydreight wants to help nurses go into business for themselves by being a turnkey solution.

We're detecting and aggressively treating more tumors than ever before. But we're also over-treating more cancers then ever.

MIT researchers have turned a system found in bacteria into programmable “nanosyringes” for injecting proteins into human cells.

A potentially lifesaving treatment to stop severe postpartum hemorrhage could soon be more accessible to the people who need it the most.

It takes around 17 years for medical research to translate into clinical practice — why not use EMR data to speed things up?

Rice University's new drug delivery tech uses biodegradable microparticles to administer medications exactly when and where they are needed.

The world needs a tuberculosis vaccine, but the challenge trials that could help are impossible to run. Two new approaches look to change that.

Using patient data and AI, French researchers have created a digital model of the brain to figure out which brain region needs removed.

New Zealand-based startup Kimer Med wants to create an antiviral that would be effective against many known viruses — and unknown.

A new peanut allergy treatment based on mRNA could potentially lead to therapies that prevent all types of allergies in people.

Naloxone administered by nasal spray can be a lifesaving drug with minimal side effects. It's now approved for over-the-counter use in the U.S.

Thanks to groundbreaking innovations in neuroscience, we’re seeing that forms of paralysis long assumed to be permanent can be reversed.

Biomedical engineer Joseph Dituri is attempting to break a world record by living in an underwater habitat for 100 days.

3D printing could make blood vessel replicas with the soft feel and the structural accuracy surgeons need.

Scientists are finding tumor signals in spit that could be key to developing diagnostic tests for various types of cancer

A groundbreaking discovery on how pancreatic cancer spreads could lead to better therapies for the hard-to-treat disease.

As avian influenza continues to devastate the bird population and jump into mammals, scientists are preparing to protect two important groups.

The FDA has approved Pfizer’s zavegepant, a nasal spray for migraines that can ease pain in as few as 15 minutes.

Researchers found that patients who slept less than six hours a night were 27% more likely to have an infection.

Canadian students launched EpiPen solution into suborbital space, and what came back was no longer life-saving medicine.

An injection of stem cells reduced the risk of heart attack or stroke by 58% in a trial of people with heart failure.

A sudden shift to virtual health care has increased access — and possibly outcomes — for patients with opioid use disorder.

It has been a year since the first COVID human challenge data was published. What did we learn, and can HCTs prepare us for the future?

A new drug might extend the lives of people with bone cancer without subjecting them to painful or unpleasant treatments.

A new stem cell therapy for Parkinson’s disease has just been administered to the brain of a person for the first time.

Massachusetts General researchers have developed a new form of transplantation that cured type 1 diabetes in monkeys.

Patients who received tirzepatide in a recent clinical study lost more than 20% of their body weight (52 pounds, or 23.6 kg).