New drug for fatty liver disease cuts fat by 65%
A new NASH treatment, efruxifermin, significantly reduced liver fat when combined with a GLP-1 drug in a small trial.
Lung cancer drug slashes patients’ risk of death by 51%
Osimertinib, an FDA-approved lung cancer drug, slashes the risk of death for certain patients by 51%, according to new trial results.
The placenta may play a role in the genetic risk of schizophrenia
Researchers at Johns Hopkins have found that genes associated with schizophrenia risk may impact the placenta, not just the brain.
Gain-of-function research is more than just tweaking risky viruses
Gain-of-function experiments in the lab can help researchers get ahead of viruses naturally gaining the ability to infect people in the wild.
Chronic pain can be objectively measured using brain signals
Even though pain is universal and we know it happens in the brain, we've never before had a way to objectively measure its intensity.
Do we finally know what causes Alzheimer’s?
The first treatments proven to slow cognitive decline in Alzheimer’s are helping settle a decades-long debate about how the disease starts.
This “bridge” between chemo and cancer solves a big problem for treatment
To improve leukemia treatment, Australian researchers have created a bispecific antibody that connects chemo drugs to cancer cells.
Cancer treatment is about to get a reboot, thanks to AI
Techniques borrowed from astrophysics are helping to advance personalized cancer treatments beyond what genetics can tell us.
Something found in bats could help us survive infections and inflammation
This protein may help bats survive viral infections and could be the springboard for new anti-inflammatory drugs.
Psychedelic inspires discovery of two new drug candidates for depression
Researchers have found ibogaine-inspired compounds effective in treating depression and addiction in mouse models.
First-in-US brain surgery performed in Boston
A surgical team has performed a surgery that alleviated a dangerous brain condition before it was too late.
Personalized mRNA vaccine preps the body to battle deadly cancer
A new pancreatic cancer vaccine based on mRNA tech was shown to be safe and capable of triggering an immune response in a small trial.
Potential way to treat anorexia found in microbiome
New research links the gut microbiome, an ecosystem of viruses, bacteria, and fungi, to the development of anorexia nervosa.
New gene therapy could reverse a common cause of blindness
A new study suggests we may be able to convert dormant eye cells into photoreceptors to reverse retinal degeneration.
Ultrasound could help us fight the deadliest cancer
In a small study, Northwestern researchers were able to get chemo drugs into the brains of glioblastoma patients with implanted ultrasound devices.
AI dramatically improved mRNA vaccines in just 11 minutes
A new AI tool can find the most stable mRNA sequence for a vaccine, leading to more effective shots that are less prone to degradation.
World’s first vaccine for RSV approved in the US
The FDA has approved the world’s first vaccine for RSV, a potentially deadly viral infection that has long eluded vaccination.
The first fecal transplant pill is heading to pharmacies
The FDA approval of the first fecal transplant pill could kick off an era in which we target the gut microbiome to treat many other diseases.
Complex brain activity detected in dying patients
Researchers have measured gamma waves, a sign of brain activity, in patients who were dying.
New Alzheimer’s drug slows cognitive decline by 35%
Eli Lilly’s new Alzheimer’s drug, donanemab, slowed cognitive decline by 35% in a phase 3 trial, but two people died from side effects.
Gene therapy reverses vision loss in primates — by making their eyes young again
A Harvard study found that a new gene therapy that reprograms cells to their younger state can reverse NAION-caused vision loss in primates.
New gel destroys brain cancer in 100% of treated mice
A new brain cancer treatment not only cured 100% of mice that received it, but also trained their immune systems to fight future cancers.
Two African countries first to approve Oxford’s malaria vaccine, with 20 million doses on the way
Ghana and Nigeria have become the first two nations to approve Oxford’s vaccine against malaria.
Hollow “seed” shrinks cancerous tumors from the inside
A new drug delivery system for pancreatic tumors could dramatically decrease medication dosages, helping minimize unpleasant side effects.
The imagination effect: A history of placebo power
The famous placebo effect has a long, rich history — it certainly had an outsized role in the medicine of centuries past.
Alzheimer’s disease: an illness that needs a long overdue cocktail
Scientists are starting to agree that the "holy grail" solution for Alzheimer's is more likely to be a drug cocktail than a single treatment.
LSD effective as major depression therapy in phase 2 trial
MindMed and University Hospital Basel have announced top line results for their phase 2 trial.
Scientists train ants to sniff out cancer in just 30 minutes
Ants were just as accurate as cancer-sniffing dogs. Better yet, they could be trained in minutes rather than months.
Study finds CPR patients may frequently have near-death experiences
In a study of CPR patients across the US and UK, researchers found new evidence about near-death experiences.
Nurses are breaking the mold to set out on their own
Tech platform Hydreight wants to help nurses go into business for themselves by being a turnkey solution.
Some cancers shouldn’t be treated
We're detecting and aggressively treating more tumors than ever before. But we're also over-treating more cancers then ever.
“Nanosyringes” can inject medicine into a single cell
MIT researchers have turned a system found in bacteria into programmable “nanosyringes” for injecting proteins into human cells.
One shot could stop severe bleeding and save thousands of lives
A potentially lifesaving treatment to stop severe postpartum hemorrhage could soon be more accessible to the people who need it the most.
One way to speed up clinical trials: Skip right to the data with electronic medical records
It takes around 17 years for medical research to translate into clinical practice — why not use EMR data to speed things up?
New drug delivery tech could ensure you never forget your meds
Rice University's new drug delivery tech uses biodegradable microparticles to administer medications exactly when and where they are needed.
Tuberculosis kills over a million people a year. New breakthroughs may help humanity fight back.
The world needs a tuberculosis vaccine, but the challenge trials that could help are impossible to run. Two new approaches look to change that.
Epilepsy surgery has a success rate of only 50%. This digital brain may change that.
Using patient data and AI, French researchers have created a digital model of the brain to figure out which brain region needs removed.
Viruses cause 200+ diseases. This one drug may be able to treat them all.
New Zealand-based startup Kimer Med wants to create an antiviral that would be effective against many known viruses — and unknown.
New mRNA therapy could bring an end to peanut allergies
A new peanut allergy treatment based on mRNA could potentially lead to therapies that prevent all types of allergies in people.
Narcan is now available over-the-counter in the US
Naloxone administered by nasal spray can be a lifesaving drug with minimal side effects. It's now approved for over-the-counter use in the U.S.
How close are we to reversing paralysis?
Thanks to groundbreaking innovations in neuroscience, we’re seeing that forms of paralysis long assumed to be permanent can be reversed.
This man is trying to live underwater for a record-breaking 100 days
Biomedical engineer Joseph Dituri is attempting to break a world record by living in an underwater habitat for 100 days.
3D-printing the brain’s blood vessels with silicone could personalize neurosurgery
3D printing could make blood vessel replicas with the soft feel and the structural accuracy surgeons need.
Saliva: The next frontier in cancer detection
Scientists are finding tumor signals in spit that could be key to developing diagnostic tests for various types of cancer
Spread of deadly cancer delayed by organ transplant drug
A groundbreaking discovery on how pancreatic cancer spreads could lead to better therapies for the hard-to-treat disease.
Bird flu is everywhere. Are the vaccines ready?
As avian influenza continues to devastate the bird population and jump into mammals, scientists are preparing to protect two important groups.
Pfizer’s nasal spray for migraines is heading to pharmacies
The FDA has approved Pfizer’s zavegepant, a nasal spray for migraines that can ease pain in as few as 15 minutes.
Here’s how your sleep affects your immune system
Researchers found that patients who slept less than six hours a night were 27% more likely to have an infection.
Canadian students discover EpiPens will turn toxic in space
Canadian students launched EpiPen solution into suborbital space, and what came back was no longer life-saving medicine.
A single injection of stem cells slashes risk of heart attack or stroke by 58%
An injection of stem cells reduced the risk of heart attack or stroke by 58% in a trial of people with heart failure.
Does online opioid treatment work?
A sudden shift to virtual health care has increased access — and possibly outcomes — for patients with opioid use disorder.
Volunteers were purposefully infected with COVID-19. Was it worth it?
It has been a year since the first COVID human challenge data was published. What did we learn, and can HCTs prepare us for the future?
New drug could extend lives of people with deadly bone cancer
A new drug might extend the lives of people with bone cancer without subjecting them to painful or unpleasant treatments.
Scientists inject stem cells into the brain of Parkinson’s patient
A new stem cell therapy for Parkinson’s disease has just been administered to the brain of a person for the first time.
New transplant technique cures type 1 diabetes in monkeys
Massachusetts General researchers have developed a new form of transplantation that cured type 1 diabetes in monkeys.
Tirzepatide: A novel obesity drug ushers in a new era of weight loss — because this one works
Patients who received tirzepatide in a recent clinical study lost more than 20% of their body weight (52 pounds, or 23.6 kg).
Oral bacteria trigger rheumatoid arthritis flare-ups
Periodontal (gum) disease is more common in individuals with rheumatoid arthritis, implicating the former in causing the latter.
First at-home test can tell you if it’s COVID or flu
The FDA has granted authorization to an at-home test that can tell COVID from flu, the first of its kind.
New MS treatment targets the gut microbiome
We may be able to prevent chronic inflammation in multiple sclerosis patients by manipulating their gut microbiomes.
Small wonders: The antibodies from camels and sharks that could change medicine
A handful of animals make a pared-down version of our own antibodies. Scientists hope to harness them as treatments for human illnesses.
New light therapy could make cancer treatment better and safer
A new light-activated cancer treatment developed in the UK could make existing therapies better and safer.
A new look at the strange case of the first gene-edited babies
Did He Jiankui "Make People Better"? A new documentary leans toward a different narrative about gene-editing than we've heard before.
This $1 pill cuts binge drinking
Naltrexone, a medication that costs less than $1 per dose, helped people cut back on their binge drinking in a small study
A single dose of an old drug could save 2 million mothers from sepsis every year
A large international study has found that a single oral dose of a common antibiotic can “significantly” reduce the risk of maternal sepsis
How diet influences the conflict between cell “cooperators” and “cheaters”
Cancer-protective microbes support cooperative behaviour by bodily cells, but cancer-inducing microbes undermine it.
New CAR-T therapy shows promise against ovarian tumors
A CAR T-cell therapy that’s effective in mice with ovarian cancer may bring us closer to using the blood cancer treatment against tumors.
Scientists have discovered how to make almost any vaccine more potent
An approach called “rational vaccinology” could allow us to design more powerful vaccines, just by rearranging their ingredients.
“Brain-eating” amoeba beaten by old European drug
A man infected by a deadly brain-eating amoeba is on the road to recovery thanks to a decades-old drug used to treat urinary tract infections.
New evidence that teeth can fill their own cavities
Researchers find that, in some cases, tooth dentin can be regrown instead of needing to be replaced with man-made composite.
ChatGPT-like AI creates new bacteria-killing proteins
Using a large language model AI, biotech startup Profluent has created new antimicrobial proteins.
Simple tweak to cancer treatment reduces relapse risk by 28%
Delivering chemotherapy to colon cancer patients before and after surgery — instead of just after — reduces their risk of recurrence by 28%.
This “ultrasound vortex” can quickly clear blood clots
Using spiraling ultrasound waves, researchers hope to remove stroke-causing blood clots faster and safer.
Microbiome-safe method could head off Staph infection
A microbiome-friendly method of controlling Staph colonization has aced phase 2 clinical trials.
New biomarker test accurately predicts who will respond to antidepressant
Alto Neuroscience’s depression drug seems effective in early trials, a proof-of-concept for biomarker-based design.
New mRNA vaccine factory is made from shipping containers
BioNTech is sending a modular mRNA vaccine factory that can produce 50 million COVID-19 vaccines annually to Africa.
Moderna’s RSV vaccine over 80% effective in early analysis
Moderna’s mRNA RSV vaccine for adults looks to be over 80% effective, based on early data from a large phase 3 trial.
Particles packed with mRNA reduce wrinkles in mice
A new delivery method for mRNA therapies could open the doors to better treatments for aging, cancer, and more.
Stanford nasal study could lead to “morning after” virus spray
A “morning after” antiviral nasal spray could be created using new knowledge about how SARS-CoV-2 invades your nose.
5 biotech trends to watch in 2023
After a monumental year of breakthroughs, scientists, investors, and CEOs share which areas of biotech they are eagerly watching this year.
New brain cancer treatment trialed in children for the first time
MRI-guided focused ultrasound has been used to deliver chemo into the brain of a pediatric cancer patient for the first time.
“Jumping genes”: A new model of Alzheimer’s
A new hypothesis suggests that Alzheimer's disease is the result of "jumping genes" in the brain, not inflammation or plaque.
Resurrecting a 2.6 billion-year-old ancient CRISPR system
Researchers have resurrected an ancient CRISPR system 2.6 billion years old, capable of editing genes in the modern day.
Google sister company aims to eradicate dengue from a tropical country
Verily, owned by Google parent company Alphabet, believes it can eliminate Singapore’s dengue problem.
The first ever honey bee vaccine has arrived
The USDA has conditionally approved a honey bee vaccine to protect the important insects from American foulbrood, a brutal bacterial infection.
Chickenpox and shingles virus lying dormant in your neurons can reactivate and increase your risk of stroke
People with shingles have an approximately 80% higher risk of stroke than those without the disease, and researchers want to know why.
FDA approves new Alzheimer’s medication
Lecanemab, a new Alzheimer’s medication shown to slow cognitive decline in patients, has been granted accelerated approval by the FDA.
Mother’s mitochondria used to treat her child’s rare genetic disorder
A new therapy that treats children with rare mtDNA mutations using mitochondria sourced from their mothers has now been tested in patients.
New mRNA universal flu vaccine against all known subtypes takes promising first steps
A new universal flu vaccine candidate that uses mRNA to target all known flu subtypes looks promising in animal models.
New stem cell patches could repair babies’ heart defects permanently
Stem cell patches under development in the UK might allow surgeons to permanently repair infants congenital heart defects.
Seven science and tech breakthroughs you may have missed this year
A roundup of major science and tech achievements that flew under the radar in 2022, including new vaccines, advanced solar cells, and more.
How to use the brain’s own immune cells to stave off Alzheimer’s
Research suggests that microglia play a key role in preventing neurodegenerative diseases by helping to remove toxic waste.
New “future-proof” drug can fight COVID-19 and the common cold
Researchers have identified a compound capable of stopping multiple coronaviruses in cell and tissue models.
First-of-its-kind therapy sends girl’s incurable cancer into remission
A first-of-its-kind CAR T-cell therapy sent a UK girl’s blood cancer into remission when all other treatments failed.
Moderna’s mRNA cancer vaccine reduces risk of recurrence or death by 44%
Moderna’s new mRNA cancer vaccine reduced melanoma patients’ risk of recurrence or death by 44% compared to a standard treatment alone.
Cheap liver drug can prevent COVID-19
A cheap, readily available drug used to treat liver disease could also prevent COVID-19 infections — regardless of the variant.
A new class of antidepressant works in 2 hours
Most types of antidepressants work by increasing neurotransmitter levels throughout the brain, which take weeks. A new drug takes hours.
Breakthrough drug cures sleeping sickness with one dose
A new, one-dose treatment for lethal sleeping sickness was 95% effective at clearing the parasite from patients.
“DALL-E 2 of biology” designs proteins for new drugs
The Chroma AI's ability to design proteins with structures no one has ever seen before could revolutionize medicine.
These tiny bubbles are “warheads” for killing cancer
By combining tiny nanobubbles with ultrasound, Israeli researchers showed they can destroy tumors.