One way to speed up clinical trials: Skip right to the data with electronic medical records
It takes around 17 years for medical research to translate into clinical practice — why not use EMR data to speed things up?
New drug delivery tech could ensure you never forget your meds
Rice University's new drug delivery tech uses biodegradable microparticles to administer medications exactly when and where they are needed.
Tuberculosis kills over a million people a year. New breakthroughs may help humanity fight back.
The world needs a tuberculosis vaccine, but the challenge trials that could help are impossible to run. Two new approaches look to change that.
Epilepsy surgery has a success rate of only 50%. This digital brain may change that.
Using patient data and AI, French researchers have created a digital model of the brain to figure out which brain region needs removed.
Viruses cause 200+ diseases. This one drug may be able to treat them all.
New Zealand-based startup Kimer Med wants to create an antiviral that would be effective against many known viruses — and unknown.
Narcan is now available over-the-counter in the US
Naloxone administered by nasal spray can be a lifesaving drug with minimal side effects. It's now approved for over-the-counter use in the U.S.
A single injection of stem cells slashes risk of heart attack or stroke by 58%
An injection of stem cells reduced the risk of heart attack or stroke by 58% in a trial of people with heart failure.
Volunteers were purposefully infected with COVID-19. Was it worth it?
It has been a year since the first COVID human challenge data was published. What did we learn, and can HCTs prepare us for the future?
Tirzepatide: A novel obesity drug ushers in a new era of weight loss — because this one works (Updated)
Patients who received tirzepatide in a recent clinical study lost more than 20% of their body weight (52 pounds, or 23.6 kg).
Small wonders: The antibodies from camels and sharks that could change medicine
A handful of animals make a pared-down version of our own antibodies. Scientists hope to harness them as treatments for human illnesses.
A new look at the strange case of the first gene-edited babies
Did He Jiankui "Make People Better"? A new documentary leans toward a different narrative about gene-editing than we've heard before.
A single dose of an old drug could save 2 million mothers from sepsis every year
A large international study has found that a single oral dose of a common antibiotic can “significantly” reduce the risk of maternal sepsis
New CAR-T therapy shows promise against ovarian tumors
A CAR T-cell therapy that’s effective in mice with ovarian cancer may bring us closer to using the blood cancer treatment against tumors.
Scientists have discovered how to make almost any vaccine more potent
An approach called “rational vaccinology” could allow us to design more powerful vaccines, just by rearranging their ingredients.
Simple tweak to cancer treatment reduces relapse risk by 28%
Delivering chemotherapy to colon cancer patients before and after surgery — instead of just after — reduces their risk of recurrence by 28%.
New biomarker test accurately predicts who will respond to antidepressant
Alto Neuroscience’s depression drug seems effective in early trials, a proof-of-concept for biomarker-based design.
Chickenpox and shingles virus lying dormant in your neurons can reactivate and increase your risk of stroke
People with shingles have an approximately 80% higher risk of stroke than those without the disease, and researchers want to know why.
Mother’s mitochondria used to treat her child’s rare genetic disorder
A new therapy that treats children with rare mtDNA mutations using mitochondria sourced from their mothers has now been tested in patients.
New mRNA universal flu vaccine against all known subtypes takes promising first steps
A new universal flu vaccine candidate that uses mRNA to target all known flu subtypes looks promising in animal models.
New stem cell patches could repair babies’ heart defects permanently
Stem cell patches under development in the UK might allow surgeons to permanently repair infants congenital heart defects.
Seven science and tech breakthroughs you may have missed this year
A roundup of major science and tech achievements that flew under the radar in 2022, including new vaccines, advanced solar cells, and more.
Moderna’s mRNA cancer vaccine reduces risk of recurrence or death by 44%
Moderna’s new mRNA cancer vaccine reduced melanoma patients’ risk of recurrence or death by 44% compared to a standard treatment alone.
Newly discovered gut bacteria may be a culprit behind rheumatoid arthritis
This bacteria is found only in the intestines of people with rheumatoid arthritis, and not in the intestines of healthy people.
New chemo pump for brain tumors could avoid side effects
A fully implantable chemo pump could help extend the lives of people with deadly brain tumors while minimizing treatment side effects.
UK study suggests single dose of monkeypox vaccine is 78% effective
A new analysis by the UK Health Security Agency has determined that one shot of a monkeypox vaccine is 78% effective at preventing infection.
New CRISPR cancer treatment tested in humans for first time
A new personalized CRISPR cancer treatment modifies the immune system's T cells to help them recognize a specific patient's tumor cells.
Good and bad memories are stored in different neurons, study finds
Positive and negative memories are stored in different parts of the brain, raising the possibility of therapeutic memory manipulation.
Injectable gel repairs severe spinal cord injuries and enables mice to walk
An injectable gel that prevents scar formation and stimulates regeneration successfully repaired severe spinal cord injuries in mice.
Study finds mindfulness as effective as medication for anxiety
An intensive form of mindfulness was found as effective as Lexapro in treating anxiety in adults in the first head-to-head comparative study.
Brain implant translates neural activity into letters, letting a paralyzed man “speak”
A new device allowed a paralyzed patient to "speak," spelling out full sentences in real-time with an error rate of about 8%.
Doctors may not be ready for blood tests that screen for multiple cancers at once
MCED tests are different from existing ones because they are trying to detect early-stage cancer, when there aren’t that many tumor cells.
African researchers push for a human challenge trial to fight TB
Tuberculosis kills over a million people a year. Researchers in Malawi are pushing for a clinical trial that may help change that.
New study will put the leading theory about Alzheimer’s to the test
Washington University in St. Louis is embarking on a drug trial that may also put the amyloid hypothesis to its ultimate test.
Organ regeneration could overcome liver failure, without a transplant
Patients wait from 30 days to over five years to receive a liver transplant in the U.S. What if the liver could regenerate itself instead?
New exercise study could find drugs that mimic working out
MIT and Harvard researchers mapped out many of the cells, genes, and cellular pathways that are modified by exercise or high-fat diet.
AI-discovered drug for ALS enters human trials in just four years
Verge Genomics has begun a trial of their AI-found ALS drug candidate, one of the first tests for this new method of drug discovery.
Australian researchers have manufactured a living blood vessel
A blood vessel isn’t just a simple tube. Researchers at the University of Sydney have developed an implant capable of mimicking its complexities.