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Spread of deadly cancer delayed by organ transplant drug
A groundbreaking discovery on how pancreatic cancer spreads could lead to better therapies for the hard-to-treat disease.
“Nature’s own Ozempic” or berberine is all over social media
Does berberine work as well as Ozempic to help people lose weight? Social media seems to think so, but it's not likely.
“I’ve been here before”: DMT study explores a strange memory phenomenon
DMT can induce a sense of profound familiarity, making users feel as if they have entered an alternate reality they have visited before.
An implantable device could enable injection-free control of diabetes
MIT engineers designed an implantable device that carries islet cells along with its own on-board oxygen factory to keep the cells healthy.
Bioengineered protein could enhance memory
Memory-related conditions are notoriously hard to treat, but there may be a way to boost recall in the brain.
Amazon’s Prime Air is coming to a new US city
Amazon’s Prime Air drone delivery service is expanding to three new cities and adding a drug-delivery option in an existing one.
New drug candidates found in an unlikely place
Costa Rica’s famed sloths harbor bacteria in their fur which can create antibiotic compounds — a potential source of future therapies.
Engineers develop a vibrating, ingestible capsule that might help treat obesity
MIT engineers designed an ingestible capsule that vibrates within the stomach, creating an illusory sense of fullness and reducing appetite.
New drug could extend lives of people with deadly bone cancer
A new drug might extend the lives of people with bone cancer without subjecting them to painful or unpleasant treatments.
Why is anxiety spiking in young people but not older adults?
Anxiety among adults 18 to 25 nearly doubled in that time period, but remained stable for adults 50 and older.
New on/off switch in mRNA lets doctors “tune” gene therapy
A new kind of mRNA switch could give doctors the ability to precisely control the expression of therapeutic genes.
New nasal spray aimed at reversing fentanyl overdoses is now approved
A new overdose-reversing spray that works fast but lasts longer has been approved by the FDA, and will be available by the fall at earliest.
Something found in bats could help us survive infections and inflammation
This protein may help bats survive viral infections and could be the springboard for new anti-inflammatory drugs.
Hollow “seed” shrinks cancerous tumors from the inside
A new drug delivery system for pancreatic tumors could dramatically decrease medication dosages, helping minimize unpleasant side effects.
“Brain-eating” amoeba beaten by old European drug
A man infected by a deadly brain-eating amoeba is on the road to recovery thanks to a decades-old drug used to treat urinary tract infections.
Netflix’s “You Are What You Eat” proves twin studies’ importance to science
What is it that makes twins so special, and how do researchers harness the power of twins? "You Are What You Eat" helps prove their importance.
Australia’s 30-year quest to unlock an ancient painkiller
A crocodile attack led to a 30-year partnership to develop a painkiller based on the Nyikina Mangala people's traditional knowledge.
Narcan is now available over-the-counter in the US
Naloxone administered by nasal spray can be a lifesaving drug with minimal side effects. It's now approved for over-the-counter use in the U.S.
Ray Kurzweil explains how AI makes radical life extension possible
Life expectancy gains in developed countries have slowed in recent decades, but AI may be poised to transform medicine as we know it.
Tirzepatide: A novel obesity drug ushers in a new era of weight loss — because this one works (Updated)
Patients who received tirzepatide in a recent clinical study lost more than 20% of their body weight (52 pounds, or 23.6 kg).
New biomarker test accurately predicts who will respond to antidepressant
Alto Neuroscience’s depression drug seems effective in early trials, a proof-of-concept for biomarker-based design.
Viruses cause 200+ diseases. This one drug may be able to treat them all.
New Zealand-based startup Kimer Med wants to create an antiviral that would be effective against many known viruses — and unknown.
To stave off Alzheimer’s, protect your brain’s mitochondria
Mitochondria are crucial for memory preservation and are emerging as key players in the fight against Alzheimer's.
First ever therapy for rare genetic disorder now approved
The FDA has approved the first drug for Rett syndrome, a genetic neurodevelopmental disorder, which disproportionately affects women and girls.
Cheap liver drug can prevent COVID-19
A cheap, readily available drug used to treat liver disease could also prevent COVID-19 infections — regardless of the variant.
Lab-grown meat techniques aren’t new
Cell cultures are common tools in science, but bringing them up to scale to meet society’s demand for meat will require further development.
DMT appears effective for depression up to six months later
Small Pharma has announced the results of a six-month follow-up for their phase 2a trial of DMT for depression.
Tiny biobots surprise their creators by healing wound
Tiny “biobots” made from human windpipe cells, amazingly, helped damaged neural tissue to repair itself in a new study.
Ancient viruses in the human genome can help fight cancer
Armed with a DoD grant, researchers are harnessing the genetic code of ancient viral infections to fight prostate cancer.
How Arc Institute is bringing science into the century of biology
Researchers at Arc Institute all work toward the same goal: make concrete progress in understanding and treating complex diseases.
New kind of pill cut “bad” cholesterol up to 60% in clinical trial
In a phase 2 trial, a daily oral medication reduced LDL cholesterol levels by up to 60%.
Ketamine is as effective as ECT for depression, study shows
A trial of patients with treatment-resistant depression found ketamine to be at least as effective as electroconvulsive therapy.
Breakthrough study discovers that psychedelics breach our neurons
Researchers have discovered that psychedelics can activate 5-HT2A receptors inside of cortical neurons, a possible cause of their therapeutic effects.
Breakthrough drug cures sleeping sickness with one dose
A new, one-dose treatment for lethal sleeping sickness was 95% effective at clearing the parasite from patients.
ADHD drugs might also treat Alzheimer’s disease
Scientists reviewed 40 years of clinical studies that assessed the effects of NA-targeting drugs, such as certain ADHD drugs, on Alzheimer’s.
Insulin grown in lettuce can be taken orally
New synthetic insulin harvested from lettuce plants can be made cheaply, taken orally, and transported at room temperature.
Scientists make pain relievers like Tylenol from pine trees rather than fossil fuels
Chemists have shown how to manufacture ibuprofen and acetaminophen using a waste product from the forestry and paper industries.
Old herpes drug helps kill deadly superbug
The anti-herpes drug edoxudine can weaken the deadly superbug K-pneumoniae, potentially offering a new weapon against antibiotic resistance.
One shot could stop severe bleeding and save thousands of lives
A potentially lifesaving treatment to stop severe postpartum hemorrhage could soon be more accessible to the people who need it the most.
New pharma supergroup aims to tackle skin disorders
Six biotech companies just merged to form Alys Pharmaceuticals with the goal of developing new treatments for skin disorders.
One shot epilepsy treatment reduced seizures by 95% in first two patients
A stem cell-based treatment for epilepsy slashed the number of seizures experienced by two trial participants by 95%.
Transplants of lab-grown brain cells reduce Parkinson’s symptoms
Transplants of lab-grown dopamine neurons reduced the amount of time people experienced Parkinson’s symptoms in a small trial.
Study suggests that exercise should be prescribed to mental health patients
Researchers concluded that exercise should be prescribed to patients with mental health issues before psychiatric drugs.
Targeted therapy kills every type of cancer in the lab
City of Hope researchers are trialing a targeted therapy shown to kill more than 70 types of cancer in preclinical tests.
A functional cure for brittle diabetes is now available in the US
Islet transplantation, a procedure shown to functionally cure some people with hard-to-control brittle diabetes, has been approved in the US.
Artificial kidney aces test in pigs
An artificial kidney prototype just aced a pig trial, bringing it closer to human trials — and a step closer to ending the need for dialysis.
Does online opioid treatment work?
A sudden shift to virtual health care has increased access — and possibly outcomes — for patients with opioid use disorder.
A single dose of an old drug could save 2 million mothers from sepsis every year
A large international study has found that a single oral dose of a common antibiotic can “significantly” reduce the risk of maternal sepsis
New fentanyl vaccine could help avoid relapses and overdoses
An in-development fentanyl vaccine that prevents the drug from entering the brain could one day help people avoid relapsing or overdosing.
LSD flashbacks and a psychedelic disorder that can last forever
LSD flashbacks have been studied for decades, though scientists still aren't quite sure why some people experience them.
Old Parkinson’s drug helps teens with type 1 diabetes
The Parkinson’s disease drug bromocriptine lowered blood pressure and reduced aortic stiffness in young people with type 1 diabetes.
Problem-solving is fundamental to human nature
Believing in the next solution is not blind optimism or even wishful thinking — it is a recognition that humans are problem-solving animals.
Do we finally know what causes Alzheimer’s?
The first treatments proven to slow cognitive decline in Alzheimer’s are helping settle a decades-long debate about how the disease starts.
Researchers engineer insulin-releasing cells that respond to sound waves
New research in mice attempts to eventually replace insulin injections with the sounds waves of rock music.
New RSV shot protects babies against dangerous lung infections
The FDA has approved nirsevimab, an RSV shot that protects babies against the leading cause of infant hospitalizations in the US.
Scientists discover “anxiety gene” in the brain — and a natural way to turn it off
The discovery of an "anxiety gene" — and a natural way to put the brakes on it — in mice could lead to new treatments for anxiety disorders.
FDA approves new Alzheimer’s medication
Lecanemab, a new Alzheimer’s medication shown to slow cognitive decline in patients, has been granted accelerated approval by the FDA.
Scientists create the first “functional” 3D-printed mini brains
The first 3D-printed brain organoids that function like natural brain tissue could lead to breakthroughs in neuroscience.
New evidence that teeth can fill their own cavities
Researchers find that, in some cases, tooth dentin can be regrown instead of needing to be replaced with man-made composite.
New chemo pump for brain tumors could avoid side effects
A fully implantable chemo pump could help extend the lives of people with deadly brain tumors while minimizing treatment side effects.
Anti-aging pill for senior dogs is now in clinical trials
An anti-aging pill for senior dogs now in clinical trials might lead to treatments that extend human lives, too.
Got COVID but felt fine? It may be your genes.
A person’s chances of having asymptomatic COVID are dramatically increased if they possess a certain genetic mutation.
Lidocaine makes cancer cells self-destruct, study finds
Lidocaine, a common local anesthetic, activates proteins that cause certain types of cancer cells to self-destruct.
Elon Musk’s Neuralink has implanted its first device in a human being
Now that Neuralink has implanted a device in a person, CEO Elon Musk is closer to his goal of making brain chips common in the future.
Experiment regenerates a damaged kidney for the first time ever
A new treatment that caused the diseased kidneys of mice to regenerate might one day do the same for people.
Injections of brain protein reverse memory loss in mice
A protein called “KIBRA” could be the key to new Alzheimer’s treatments that don’t just slow disease progression, but reverse memory loss.
Australian ant honey inhibits tough pathogens, new research shows
Honeypot ant honey may help develop our arsenal of effective antibacterial and antifungal treatments, which are increasingly vital.
Serotonin plays a key role in patience and impulse control, research says
Evidence suggests that there is in fact a neurological factor to the brain's ability to control impulses and manage patience.
A magnetic therapy for depression gains precision
Approved over a decade ago, transcranial magnetic stimulation (TMS) could be effective if the treatment was tailored to individual brains.
Have scientists found a “brake pedal” for aging?
A new protein discovery may have highlighted a "switch" in brain cells that slows down inflammation and aging.
New study will put the leading theory about Alzheimer’s to the test
Washington University in St. Louis is embarking on a drug trial that may also put the amyloid hypothesis to its ultimate test.
A new class of antidepressant works in 2 hours
Most types of antidepressants work by increasing neurotransmitter levels throughout the brain, which take weeks. A new drug takes hours.
First-of-its-kind pig kidney transplant is a success
A woman with heart and kidney failure is now the second person in the world to undergo a gene-edited pig kidney transplant.
“DALL-E 2 of biology” designs proteins for new drugs
The Chroma AI's ability to design proteins with structures no one has ever seen before could revolutionize medicine.
Why do women live longer than men?
Women tend to live longer than men around the world – but the gap life expectancy is not a constant. These stats tell the story.
CRISPR uncovers possible antidote for death cap mushroom poisoning
Researchers have figured out how the mushroom's main toxin enters human cells — and maybe how to stop it.
Study finds mindfulness as effective as medication for anxiety
An intensive form of mindfulness was found as effective as Lexapro in treating anxiety in adults in the first head-to-head comparative study.
The imagination effect: A history of placebo power
The famous placebo effect has a long, rich history — it certainly had an outsized role in the medicine of centuries past.
New AI generates CRISPR proteins unlike any seen in nature
An AI that generates CRISPR proteins is opening the door to gene editors with capabilities beyond what we’ve found in nature.
Epilepsy surgery has a success rate of only 50%. This digital brain may change that.
Using patient data and AI, French researchers have created a digital model of the brain to figure out which brain region needs removed.
New Alzheimer’s drug slows mental decline by 27% in clinical trial
Eisai and Biogen are reporting that their new Alzheimer’s antibody slowed cognitive decline by 27% in a global trial.
5 drugs that changed the world (and what went wrong)
Anesthesia, penicillin, antibiotics, diazepam, and the birth control pill have all radically changed our lives.
Meth addiction treatments are finally on the horizon
New antibody and drug therapies may soon help treat meth patients, who currently have no pharmacological interventions.
An old anti-psychotic offers a new way to treat chronic pain
Researchers have found that an old anti-psychotic drug may have implications for chronic pain and cancer.
Why is the value of money for happiness increasing?
While the old adage says that money can’t buy happiness, studies have determined that the more your income increases, the happier you are.
Biden pardons federal cannabis possession cases, urges states to do the same
The Biden administration is pardoning federal possession offenses, encouraging states to do the same, and reexamining its drug scheduling.
New “future-proof” drug can fight COVID-19 and the common cold
Researchers have identified a compound capable of stopping multiple coronaviruses in cell and tissue models.
New exercise study could find drugs that mimic working out
MIT and Harvard researchers mapped out many of the cells, genes, and cellular pathways that are modified by exercise or high-fat diet.
Organ regeneration could overcome liver failure, without a transplant
Patients wait from 30 days to over five years to receive a liver transplant in the U.S. What if the liver could regenerate itself instead?
Tuberculosis kills over a million people a year. New breakthroughs may help humanity fight back.
The world needs a tuberculosis vaccine, but the challenge trials that could help are impossible to run. Two new approaches look to change that.
A new drug could repair stroke damage to memory and movement
A new drug can repair stroke damage in mice, improving memory and motor skills. If it works in humans, it could lead to a paradigm shift in stroke treatment.
The psychedelic DMT causes the brain to become hyperconnected, scans reveal
Researchers gave 20 healthy subjects potent, intravenous doses of the psychedelic DMT and observed their brains. Here's what they found.
Withdrawal symptoms from antidepressants can last over a year
A scientific review found that withdrawal symptoms from antidepressants and antipsychotics can last for over a year.
T-Minus: Counting down the top 10 space stories of 2024
A look back on the 10 greatest space stories of 2024, from SpaceX's "Mechazilla" to a first-of-its-kind civilian spacewalk.
New kind of schizophrenia drug aces human trial
KarXT, a new schizophrenia treatment that addresses a wider range of symptoms than existing meds, has aced a phase 3 trial.
Biggest science prize in history aims to extend human healthspan by a decade
Do humans have an ethical obligation to “die young”? Maybe not in the way you think, says bioethicist Raiany Romanni.
HIV drug could improve memory
The common HIV drug maraviroc improved memory linking in aging mice and might be able to help people experiencing memory loss, too.
Archaeologists identify contents of ancient Mayan drug containers
Archaeologists used new methods to identify contents of Mayan drug containers, discovering a non-tobacco plant.
How the “powerhouse of the cell” could be cancer’s Achilles heel
Salk Institute researchers have found that rewiring mitochondria could make cancer cells visible to the immune system.