This “living medicine” can eliminate a deadly lung infection
Researchers have engineered bacteria to create a “living medicine” against a nasty respiratory bug.
5 biotech trends to watch in 2023
After a monumental year of breakthroughs, scientists, investors, and CEOs share which areas of biotech they are eagerly watching this year.
Study finds 155 tiny new genes evolving in humans
Microproteins encoded in short strands of DNA reveal our recent evolutionary history, and hint at how human genetics may be changing.
“Jumping genes”: A new model of Alzheimer’s
A new hypothesis suggests that Alzheimer's disease is the result of "jumping genes" in the brain, not inflammation or plaque.
Resurrecting a 2.6 billion-year-old ancient CRISPR system
Researchers have resurrected an ancient CRISPR system 2.6 billion years old, capable of editing genes in the modern day.
A single injection of gene therapy made old mice live 7% longer
Biotech startup Rejuvenate Bio says it has extended the lives of elderly mice by 7% using a technique called “partial reprogramming.”
Mother’s mitochondria used to treat her child’s rare genetic disorder
A new therapy that treats children with rare mtDNA mutations using mitochondria sourced from their mothers has now been tested in patients.
Genetic research confirms your dog’s breed influences its personality — but so do you
A dog's breed has a big impact on their personality, but whether they fit your lifestyle is also down to good training.
New antibody therapy works for 73% of multiple myeloma patients
A new multiple myeloma therapy that uses an antibody to bring T cells to the cancer has shown efficacy in clinical trials.
Startup unveils $179 houseplant engineered to purify your air
Neoplants' $179 genetically engineered houseplant pulls VOCs from the air 30 times more efficiently than plants found in nature.
Deadly disease treated in the womb for the first time
In a medical first, doctors were able to prevent heart and muscle damage using enzyme replacement therapy.
$3.5 million treatment for hemophilia wins FDA approval
The FDA has approved biotech company CSL Behring's Hemgenix, a hemophilia B treatment that costs $3.5 million per dose.
Engineered bacteria may fight this brain-damaging genetic disorder
A possible phenylketonuria therapy using engineered bacteria has shown positive results in a small phase 2 trial.
Understanding cancer’s “dark matter”
Researchers have discovered that cancer’s epigenome — changes to how genes are expressed that aren’t mutations — may play a key role in its behavior.
What you eat can reprogram your genes
You are what you eat, and what your parents ate, and what their parents ate. An expert explains how the foods you eat can reprogram your genes.
UK scientists solve a decades-long blood mystery
Researchers have discovered a new blood group which may have been behind the tragic loss of two babies.
Like genes, your gut microbes pass from one generation to the next 
Not only did microbes diversify with their early modern human hosts as they traveled across the globe, they followed human evolution.
Genetically engineered bacteria make living materials for self-repairing walls and cleaning up pollution 
With just an incubator and some broth, researchers can grow reusable filters made of bacteria to clean up pollution and more.
A newly discovered class of RNA can fight off multiple viruses, including flu and SARS-CoV-2
Harvard-affiliated researchers have discovered a form of double-stranded RNA which may be a potent antiviral.
Shape-shifting DNA is helping researchers decode the human brain
Researcher Nako Nakatsuka has turned to DNA to tackle an important challenge: how do we measure chemicals in the brain?
World’s first cloned arctic wolf is now 100 days old
After two years of effort, China's Sinogene Biotechnology has created the world’s first cloned arctic wolf.
Identical twins were raised in different countries. Here’s how they differ today.
After being separated as toddlers, two identical twins were raised apart in the US and South Korea.
Woman with rare gene mutations feels no pain, anxiety
A woman in Scotland was found to feel virtually no pain and report zero trace of any anxiety or depression.
Breakthrough in photosynthesis boosts plant growth up to 30% 
In a small study, researchers have engineered soy plants to have higher yields thanks to improved photosynthesis.
An international team sets out to cure genetic heart diseases with one shot
Researchers from the UK, US, and Singapore are beginning work on a genetic heart cure they hope to begin clinically testing within five years.
First personalized CRISPR therapy approved for trial
The FDA has approved a trial for the first personalized CRISPR therapy, which was developed to treat Duchenne muscular dystrophy.
Which microbes live in your gut? A microbiologist tries at-home test kits
A microbiologist looks at how home test kits work, what kind of information they provide and if they can really help change your gut.
Cells become zombies when the ends of their chromosomes are damaged
Damage to the ends of the chromosomes can create “zombie cells” that are still alive but can’t function, researchers say.
Transhumanism: Savior of humanity or false prophecy?
While many of the technologies upon which transhumanists base their dream are real and world-changing, they have major limitations.
How natural “short sleepers” thrive on 4 hours of sleep per night
Natural "short sleepers" thrive on only four to six hours of sleep per night. Could their genetics explain why?
Your genes may impact psychedelic experiences 
UNC researchers have found evidence that the genetic makeup of a crucial receptor may impact your psychedelic experience.
Large study of 20,000 cats and dogs could help pets live longer 
Mars Petcare has announced the opening of a massive biobank to study aging and pet diseases.
Potential cause of unexplained epilepsy cases uncovered
University of Arizona researchers have uncovered a protein that might be behind some epilepsy cases with currently unknown causes.
“Soft CRISPR” is safer and could help cure more diseases
A new CRISPR system was far more effective and precise than CRISPR-Cas9 when tested in fruit flies.
CRISPR cure for high cholesterol enters first human trial
A trial testing a new CRISPR-based treatment to lower cholesterol has officially kicked off in New Zealand.
An old HIV drug may treat Down syndrome 
A common HIV drug could potentially be a Down syndrome treatment, improving cognition in mouse models of the condition.
Gene editing gone wrong: Scientists accidentally create angry hamsters
A team of scientists used gene editing to create what they thought would be a calmer rodent. Instead, the gene-edited rodents were angrier.
CRISPR cure for sickle cell nearly 100% effective after three years
A CRISPR therapy for sickle cell disease and beta thalassemia looks close to 100% effective three years after infusion.
A groundbreaking solution could unleash our hydrogen future
German researchers have created genetically engineered bacteria that can rapidly store and release hydrogen fuel.
New CRISPR-based map ties every human gene to its function 
Researchers used a single-cell sequencing tool Perturb-seq on every expressed gene in the human genome, linking each to its job in the cell.
The age reversal tech that billionaires are banking on
How long can a human being not only live but thrive? A race to find out involves some of the biggest names (and bank accounts) in tech.
Gene therapy fixes rare heart disorder with clever workaround
Cleveland Clinic researchers have developed a gene therapy that cured arrhythmias in mice.
Chinese robot clones pigs with no human help
A robot that automates a common technique for animal cloning has been used to produce a litter of pigs in China.
A new treatment may cure neuropathic pain
A gene therapy tested in animals may be a safe, permanent, and non-addictive treatment for neuropathic pain in humans.
Genetic mutations can be benign or cancerous – here’s a new way to identify them
Identifying the difference between normal genetic variation and disease-causing mutations is vital for determining a person's treatment.
Gene editing could reverse anxiety and alcohol-use disorder 
Gene editing may be a treatment for anxiety and alcoholism in adults who were exposed to binge-drinking in their adolescence.
How herpes wakes up
Researchers believe they have identified how herpes hiding in your cells wakes back up to cause symptoms.
Genes from over 5,000 stroke patients hint at surprising treatment
A study of nearly 6,000 stroke patient genomes suggests a treatment idea abandoned for decades should get a second look.
A Spanish teen’s genome may hold the secret to lupus
Researchers believe they have found a single point mutation in an infection-sensing gene that causes the autoimmune disorder.
How Robert Langer, a pioneer in delivering mRNA into the body, failed repeatedly but kept going
Langer published the first paper to show that it was possible to deliver nucleic acids like RNA and DNA to the body via tiny particles.
This wristband tells you what food to buy based on your DNA
By analyzing genetic code determining susceptibility to health conditions like diabetes, it tells you which foods are best for you.
An ancient enzyme could supercharge photosynthesis
Researchers have resurrected an ancient version of the enzyme Rubisco in the hope of supercharging photosynthesis in today’s plants.
Mutations in 16 species reveal clues to human aging
A surprising pattern in how often mammal cells undergo somatic mutations could be a boon to longevity research.
Researchers identified over 5,500 new viruses in the ocean
These discoveries help scientists better understand not only the evolutionary history of viruses but also the evolution of life on Earth.
CRISPR could create hypoallergenic cats
The results of a recent study found that genetically engineering cats could be a solution to eliminating cat allergies.
One breed of honey bee can survive its deadliest threat
A line of honey bees bred to resist the Varroa mite parasite has proven itself in a large-scale trial involving more than 350 bee colonies.
Should we use genome editing to make better babies?
Over the years, many different people, from preachers to philosophers, have voiced their concerns over the safety and ethics of gene editing.
Purple tomatoes could soon hit store shelves
Purple tomatoes modified to be packed with antioxidants found in blueberries could soon be approved for sale by the FDA.
Wounds of kids with “butterfly disease” healed by DNA gel
A topical gene therapy helped heal the wounds of people with “butterfly disease,” a painful disorder that makes the skin incredibly fragile.
This “family tree of all of humanity” shows how all of us are linked
Researchers have mapped the genetic ties between every person who ever lived, in the "first draft" of our shared family history.
Elephant tusk DNA is used to expose poaching networks
Researchers using cell phone records, shipment logs, and elephant DNA have solved poaching mysteries and identified trafficking networks across the continent.
Clues to schizophrenia and bipolar disorder hidden in the dark genome 
A new study suggests that the causes of these disorders are hidden in "dark genes," which may account for the enigma of their development.
How mRNA and DNA vaccines could treat autoimmune disorders, genetic diseases, and more
Using DNA or an mRNA vaccine, researchers are investigating the feasibility of essentially replacing missing genes that cause disease.
Golden blood: The rarest blood type in the world
Golden blood, despite sounding like medical nonsense, is actually the nickname for Rh-null, the world’s rarest blood type.
DNA used to make the world’s tiniest “radio” 
Scientists have created the world's smallest antenna, measuring only five nanometers in length. It is designed to decipher real-time changes in proteins and records and transmits data via light signals.
First gene therapy for Tay-Sachs disease successfully given to two children
After 14 years in development, gene therapy has helped two children surpassed their life expectations and live seizure-free.
New breed of pig will provide organs for human transplantation 
German researchers are breeding a new type of pig that’s been genetically modified to have organs ideal for human transplantation.
Gene therapy shows promise at treating severe form of epilepsy
A new Dravet syndrome treatment that targets genes could help extend the lives of people with the rare, but severe form of epilepsy.
What HIV & Amish DNA can tell us about staying healthy longer
Northwestern University has launched a new longevity research center where scientists will look for ways to combat biological aging.
What the ancient, alien jellyfish can tell us about the human brain
The jellyfish nervous system, revealed by glowing genes, may help unlock the secrets of how our own brain evolved.
Would we still see ourselves as “human” if other hominin species hadn’t gone extinct?
It’s all well and good to discuss how our humanity evolved – but what even is humanity?
Survival genes from the world’s harshest desert environment could save our crops
Researchers have discovered genes linked to plant survival in Chile's Atacama Desert, one of the world's harshest desert environments.
Lizard regenerates perfect tail thanks to stem cells
A USC study that prompted lizards to regenerate tails that were “perfect” could help facilitate breakthroughs in human regeneration.
Can the woolly mammoth save Siberia from climate change?
Harvard geneticist George Church’s new de-extinction startup aims to resurrect the woolly mammoth to help combat permafrost thaw.
mRNA cancer treatment shrinks tumors in mice
An mRNA cancer treatment in human trials has proven incredibly effective in mice, shrinking tumors in 85% of the rodents tested.
Forensic scientists continue mission to identify 9/11 victims
Forensic scientists have identified two more 9/11 victims and will soon use next-generation sequencing to analyze unidentified remains.
Brain-wide gene editing may one day treat Alzheimer’s
Researchers have developed a brain-wide gene editing technique that treated Alzheimer’s disease in mice.
Scientists are vacuuming DNA from the air to study biodiversity
Researchers have proven that the atmosphere contains measurable amounts of eDNA, and they can vacuum it from the sky.
Kenya’s GM cassava plant gets greenlight
Kenya is moving forward with developing a cassava plant that’s been genetically modified to resist cassava brown streak disease.
Permanent hearing loss may be reversible
A new mouse study suggests we may be able to reverse permanent hearing loss in humans by tapping into a latent regenerative ability.
Adding one gene to rice and potatoes increased yields by 50%
The insertion of a gene found in animals prompted potato and rice plants to produce 50% more food and exhibit drought-resistant qualities.
New treatment reverses age-related memory loss in mice
A treatment that reversed age-related memory loss in mice could one day treat or prevent such cognitive decline in older people.
Ancient human’s genome sequenced from DNA in cave dirt
Researchers have sequenced the genome of one of the ancient humans who lived in Satsurblia Cave 25,000 years ago using samples of cave dirt.
Cholera vaccine made from GM rice passes first human trial
An oral cholera vaccine that’s grown in genetically modified rice and can be stored at room temperature has passed its first human trial.
Editing one gene extends mouse life expectancy by 23%
By modifying just one gene, researchers were able to extend the life expectancy of mice by 23%, and they think their results may translate to humans.
The entire human genome has (finally) been sequenced
Researchers have finally sequenced the complete human genome, filling the gaps in the Human Genome Project’s historic first draft.
Gene therapy and special goggles partially restore man’s vision after 40 years
Researchers have demonstrated that restoring limited vision to people suffering from retinitis pigmentosa, a historically permanent type of blindness, is within reach.
The DNA-based diet you’ll be hearing about everywhere
A growing field called "nutrigenomics" aims to provide people with personalized lifestyle guidance based on their DNA
Gene therapy appears to cure “bubble boy disease”
A new gene therapy designed to treat children with ADA-SCID, a form of “bubble boy disease,” was incredibly successful in trials.
1 billion genetically modified mosquitoes will be released in the U.S.
Oxitec recently released genetically modified mosquitoes on three of the Florida Keys. The idea is that they will curb the spread of diseases by decreasing populations of Aedes aegypti.
Supercentenarians’ DNA reveals clues to human longevity
A human longevity study involving people over the age of 105 has found that genetic variants linked to DNA repair appear to contribute to a longer life.
These plants have been genetically modifying themselves for decades
New evidence shows that plants have been genetically modifying themselves for decades in a process called lateral gene transfer.
This spit test will help couples know their baby's risk of genetic disease
A new genetic test offers prospective parents a "polygenetic risk score," or an estimate of their potential offspring's predisposition to certain conditions.
A single gene turns on humans' rapid brain growth
Researchers have looked at gene expression in human brain organoids compared to other apes to discover the genetic mechanism crucial to triggering the human brain's rapid growth.
Penn scientists correct genetic blindness with a single injection into the eye
Antisense oligonucleotide therapy uses small molecules to alter RNA. Researchers have now used those molecules to alleviate a genetic form of blindness.
A major Huntington’s trial has failed. Here’s why there is still hope.
A simple genetic test can determine a person's fate for one of the worst diseases on the planet. But research offers new hope for Huntington's disease.
Argentina’s songbirds explain a mysterious type of speciation
With the help of a group of songbirds, researchers have uncovered the mystery of an evolutionary process called “sympatric speciation.”
This insect swiped a gene from plants to help itself survive
A plant gene has been discovered in whiteflies, marking the first known example of horizontal gene transfer of a functional gene between plants and insects.
“Zombie” cells grow in the brain after death
After death, gene expression increases in the brain’s glial cells — and those “zombie” cells could affect how we study neurological disorders.
A virus invisibility cloak makes AAV gene therapy safer
Researchers have figured out a way to cloak the AVV so it can sneak past the human immune system and deliver its gene therapy payload undetected.