Field: Public Health
“LEGO-like” vaccine protects mice from COVID, SARS, MERS, and variants
Using a “chimeric” spike protein, researchers have immunized mice against multiple types of coronaviruses with one shot.
A new superbug strategy
Researchers at the University of Geneva have a new idea on how to stop superbugs: don’t kill them.
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Just Might Work
Biohackers take aim at big pharma’s stranglehold on insulin
These biohackers plan to give away their instructions for how to make insulin for free.
We may have a new ally in the fight against dengue fever
A large trial has provided the best evidence yet that infecting mosquitoes with Wolbachia can help reduce dengue infections.
A virus "chimera" reveals new dengue targets
Using a flavivirus that only infects insects, Australian researchers can safely study more dangerous viruses.
Did the flu lose diversity during the pandemic?
After a record-low flu season, an entire clade of flu may be gone. If so, making vaccines may have become easier.
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Just Might Work
Can we hack sugar to be healthy?
Is there such a thing as healthy sugar? Food scientists in Israel are hacking the sugar molecule itself – eliminating the need for subpar alternatives.
Moderna COVID-19 vaccine 2.0: Lower dose, fewer side effects
Any revised version of the Moderna COVID-19 vaccine will likely include a smaller dose, reducing side effects and increasing the supply of shots.
Can a dog vaccine for Valley fever lead to a human one?
Cases of Valley fever, a fungal infection, have risen dramatically over the decade. Researchers hope a dog vaccine may lead to one for humans.
Mass vaccination experiment was a huge success in Brazil
A mass vaccination experiment in Brazil suggests that even a moderately effective vaccine can have a dramatic effect if enough people get the shot.
Dengue fever vaccine still protects after three years
A dengue fever vaccine candidate by Takeda is still effective after three years in a large human study, raising hopes for fighting the virus.
One-minute COVID-19 breath test authorized in Singapore
Singapore has provisionally authorized a COVID-19 breath test that measures VOCs to deliver accurate results in just one minute.
Ohio announces $1M vaccine lottery, shots surge 33%
Ohio’s vaccine lottery, which will give five vaccinated residents $1 million each, appears to have sparked the desired increase in new vaccinations.
Can an app save cardiac arrest victims before EMS arrives?
In Denmark, Heartrunner directs citizen responders to cardiac arrest victims. Should the U.S. adopt a similar approach?
Can new drugs make obesity a medical — not moral — condition?
Researchers are hopeful that a class of drugs called incretins will not only treat obesity, but help people think of it as a medical condition.
Your incentives to get the COVID-19 vaccine
If protection against a potentially deadly virus isn’t enough, there are these added incentives to get the COVID-19 vaccine.
Desiging a better condom
Around the world, new materials and approaches are being studied as researchers look to create the condom 2.0.
Would you spray this DIY COVID-19 vaccine up your nose?
Makers of a DIY COVID-19 vaccine are talking to governments about launching human challenge trials to quickly and cheaply find out if the vaccine is effective.
How long are you too high to drive? The science is fuzzy.
Some drug driving laws outlaw any amount of THC. To create better laws, researchers are trying to find out how long cannabis intoxication itself lasts.
Oxford malaria vaccine is 77% effective in young children
A malaria vaccine developed by Oxford University was 77% effective at protecting children during a phase 2 trial in Africa.
Can CBD be the next superbug slayer?
In the search for new weapons against superbugs, CBD and antibiotics in combination, as well as CBD alone, may prove to be promising candidates.
All adults in the US are now eligible for COVID-19 vaccines
In the U.S., anyone over the age of 16 is now eligible for COVID-19 vaccines — a major milestone along the path to herd immunity.
Food supplement appears to “cure” malnutrition in children
A food supplement designed to cure malnutrition in children doesn’t just deliver calories — it also helps promote a healthy gut microbiome.
New approach for mRNA HIV vaccine passes first human trial
There is currently no HIV vaccine, but a new technique which produced specific immunity cells in humans may pave the way to one.
Pfizer’s COVID-19 vaccine 100% effective in adolescent study
Pfizer’s COVID-19 vaccine was reportedly 100% effective in a trial involving more than 2,000 adolescents between the ages of 12 and 15.
A common virus may be the key to a COVID vaccine for young children
Researchers have reverse-engineered a common children’s virus to show the spike protein, potentially leading to a new COVID vaccine for young children.
US will spend $1 billion studying long COVID
The U.S. is dedicating $1.15 billion to studying long COVID, a condition in which survivors experience long-term effects of COVID-19.
New test can show if you’ve had COVID-19, even if antibodies fade
The FDA has approved a T cell test for COVID, a first-of-its-kind assay that looks to the immune system’s memory.
Can RNA create a malaria vaccine?
An effective malaria vaccine could save hundreds of thousands of lives each year. Can RNA vaccines like the ones fighting SARs-CoV-2 tackle another disease?
Smartphones can track your blood sugar levels
The ability to easily monitor blood sugar levels would allow everyone to have more control over their own metabolic health — not just people with diabetes.
Cone snail venom may help treat malaria
Clumps of infected red blood cells can make malaria dangerous even after its parasite is treated. Cone snail venom may one day help.
A new bird flu is infecting people. Here’s what we know.
The H5N8 bird flu virus has reportedly infected seven poultry farm workers in Russia. Here’s what we know about the new avian flu threat.
FDA: One-shot COVID-19 vaccine is safe and effective
FDA experts confirm that Johnson and Johnson’s one-shot COVID-19 vaccine is safe and effective, putting it a step closer to authorization.
World’s first COVID-19 human challenge study is a go
Researchers have gotten the green light to deliberately infect people with the coronavirus as part of the world’s first COVID-19 human challenge study.
The hunt for a universal coronavirus vaccine
A universal coronavirus vaccine that protects against multiple coronaviruses could stop the next potential pandemic from ever starting.
Study: Strong immunity without Pfizer vaccine’s second dose
The Pfizer vaccine's second dose might not be as necessary as thought — and ultra-cold storage of the COVID-19 vaccine might not be necessary at all.
Tracking heart health at home
In partnership with Omron
Can new technology help society eliminate cardiac episodes completely?
Fauci predicts universal COVID-19 vaccine availability by April
Anthony Fauci expects April will be “open season” for COVID-19 vaccines. Here’s why his prediction about COVID-19 vaccine availability appears accurate.
Are we scratching the surface of what an old vaccination method can do?
Smallpox vaccine was administered by scratching the skin. Mice suggest this old-school method may work better against other respiratory viruses as well.
Predicting which birds can cause Lyme disease spread
Lyme disease spreads via infected ticks, some of whom pick it up from birds. But which birds may carry the disease to new places?
New discovery could stop dengue’s “breakbone” fever
Making a dengue vaccine is difficult. It’s early, but a new antibody that targets a protein the virus makes instead of the virus itself may be a solution.
Vaccines and recovery both provide strong COVID-19 immunity
Natural COVID-19 immunity — the kind coronavirus survivors have — is about as robust as the immunity prompted by vaccines.
These are the medical breakthroughs that inspired us in 2020
2020 has put medicine to the forefront like never before. Freethink’s B. David Zarley looked back on the year and chose three medical developments that inspired him.
The new coronavirus mutation: What we know & what we need to figure out
A new coronavirus mutation is spreading quickly in the U.K. Here’s what we know about the coronavirus strain and what we need to figure out.
Tobacco-based COVID-19 vaccine moves to human trials
British American Tobacco has FDA approval to begin human trials on a tobacco-based COVID-19 vaccine that could potentially be stored at room temperature.
Your questions about the Pfizer COVID-19 vaccine answered
If you have questions about the COVID-19 vaccine approved for use in the U.S., this is your place to find answers.
A universal flu vaccine has aced phase 1 trials
Influenza’s constant genetic shifting means flu vaccines aim at a moving target. But a universal flu vaccine just passed its phase 1 trials.
HIV can hide inside human cells for years. Can CRISPR cut it out?
Using CRISPR to stop the replication of SIV, a primate virus closely related to HIV, researchers may have taken a step to wiping the virus out in the body.
FDA authorizes first over-the-counter COVID-19 test
The FDA has authorized the first over-the-counter COVID-19 test for home use, but buyers still have to send their samples to a lab for processing.
The quest for a “warm” COVID-19 vaccine
Developers are on the hunt for a warm COVID-19 vaccine, one that could be distributed in places where a reliable cold chain isn’t available.
Congo just used vaccines to beat Ebola. What they learned could stop COVID, too.
Congo’s recent success delivering frigid Ebola vaccines to remote areas may provide invaluable experience for a COVID-19 vaccine cold chain.
When will we have a COVID-19 vaccine?
Several developers have reported incredible coronavirus vaccine progress, so when will we have a COVID-19 vaccine ready for distribution?
Reverse engineering a $15k medical device for 50x less
Many hospitals in developing countries can’t access the overpriced, high-tech equipment that’s standard in the U.S. Reverse innovation could finally change that.
Oxford says its COVID-19 vaccine is up to 90% effective
The University of Oxford's COVID-19 vaccine was up to 90% effective in a phase 3 trial and could be easier to distribute than other coronavirus vaccines.
How long will coronavirus immunity last?
Coronavirus immunity might last for years, according to a new study that measured the levels of virus-fighting immune cells in COVID-19 survivors.
FDA authorizes first at-home COVID-19 test
The FDA has authorized an at-home COVID-19 test that delivers results in 30 minutes, but you can’t get it without a prescription.
Trial suggests Moderna’s coronavirus vaccine is 95% effective
Another win for mRNA vaccines: Moderna’s coronavirus vaccine appears to be 94.5% effective at preventing COVID-19, according to initial trial data.
A flu vaccine grown in tobacco plants just aced its clinical trials
Plant-based vaccines can be made cheaply and at scale. A tobacco plant-based vaccine for influenza has now been the first to complete clinical trials.
Finally! A smart toilet offers fecal testing for the masses
Fecal testing can reveal a surprising amount of medical data. Israeli startup OutSense wants to do so from your home.
Can a new polio vaccine help finish the virus off once and for all?
Thanks to polio vaccines and public health campaigns, polio is on the run — although COVID has it fighting back. Can a new vaccine help turn the tide again?
“Virus burritos” could be the key to vaccine preservation
Vaccine preservation is crucial to world health; the WHO estimates we waste 50% of vaccines a year. Vaccine burritos may provide some help.
Pfizer COVID-19 vaccine appears 95% effective (updated)
The Pfizer COVID-19 vaccine appears to be 95% effective at preventing coronavirus infections, according to an early analysis of a Phase 3 trial.
"Autoantibodies" may be causing COVID-19 blood clots
COVID-19 blood clots may be caused by autoantibodies, which attack the body’s own tissues and organs instead of intruders.
What’s going to happen with COVID-19 this winter?
There may be an increase in cases of COVID-19 this winter as people move indoors, but there are actions we can take to prevent it.
Cough-analyzing AI detects asymptomatic COVID-19 infections
MIT has developed an AI that can detect asymptomatic COVID-19 infections from the sound of a person’s forced-cough with incredible accuracy.
How to safely celebrate Halloween during COVID-19
People celebrated Halloween during the 1918 flu pandemic and you can still celebrate Halloween during COVID-19 — just maybe not the way you usually do.
Can flu vaccines prevent COVID-19?
Researchers suspect that flu shots could prevent coronavirus infections, giving people yet another reason to get vaccinated.
A pandemic surveillance system for the planet
In partnership with Skoll Foundation
COVID-19 won’t be the last virus to threaten the global population, but new disease surveillance tech could catch the next outbreak before it even starts.
UK to launch first human challenge trial for COVID-19
The U.K. is funding a $44 million human challenge trial for COVID-19 during which healthy volunteers will be deliberately exposed to the coronavirus.
A deadly virus emerged in South Africa in 2008. Then it vanished.
A deadly new virus killed a South African safari agent and three others, then disappeared without a trace. What can we learn from a unique outbreak?
Patients report sudden hearing loss from COVID-19
Patients are experiencing sudden hearing loss from COVID-19, but if caught early enough, doctors can prevent the problem from becoming permanent.
The coronavirus can survive on surfaces for 28 days
The coronavirus can survive on surfaces, including money, for up to 28 days. But does that change what you need to do to avoid catching COVID-19?
Post-COVID-19 clinics offer hope to coronavirus survivors
Post-COVID-19 clinics are helping coronavirus survivors cope with lingering symptoms while helping researchers better understand the disease.
Comparing COVID-19 vaccines just got way easier
A newly formed network of labs will make it easier to compare COVID-19 vaccines by testing them all in exactly the same way, using the exact same supplies.
Pain relief from coronavirus may be helping it spread
Rather than feeling sick, some people may be getting pain relief from coronavirus — a discovery that could impact both the pandemic and the opioid epidemic.
A new molecule may take the edge off vaccines — and make them perform better
Adjuvants create a better vaccine immune response, but they also cause inflammation. A peptide may help curb their side effects while improving protection.
Coronavirus nasal spray vaccine nears human trials
A nasal spray vaccine for COVID-19 that contains a live coronavirus genetically engineered to replicate more slowly is nearing human trials.
Johnson & Johnson’s COVID-19 vaccine reaches final trial stage
Johnson & Johnson’s COVID-19 vaccine isn’t the first to reach the final human trial stage, but it may have several advantages over its predecessors.
Studying pig sh*t to prevent the next pandemic
A pilot program in North Carolina offers one solution to scanning for a potential pig virus in our farm system - slurry testing.
This edible sensor can alert you of food contamination
A microneedle patch made of silk changes color if it senses food contamination or spoilage, making it easier to know when food’s gone bad.
What we know about COVID-19 reinfection so far
Researchers have reported four cases of COVID-19 reinfection, with patients recovering from the coronavirus and later testing positive for another strain.
A patient’s sex may affect their COVID-19 immune response
Key differences in the COVID-19 immune response of men and women could potentially explain a disparity in patient outcomes.
Influenza virus may be transmitted by particles in the air
Airborne particles like dust and dander not caused by breathing — “aerosolized fomites” — may be a route of influenza virus transmission.
$5 COVID-19 test could be a game changer in the US
Abbott Laboratories’ $5 COVID-19 test has secured an FDA authorization, meaning the U.S. now has access to a fast, accurate antigen test.
“Antivitamins” could be the cure for antibiotic resistance
The B1 antivitamin helps bacteria kill competing bacteria, leading researchers to suspect it could help us fight antibiotic resistance and superbugs.
Open-source COVID-19 saliva test could be a game changer
SalivaDirect, a COVID-19 saliva test funded by the NBA and NBA players’ union, could be the cheap, accurate testing method the U.S. desperately needs.
Gates Foundation backs a $3 coronavirus vaccine
The Gates Foundation is spending $150 million to help with the manufacturing and distribution of a $3 coronavirus vaccine in lower-income nations.
Is it safe to fly right now? MIT expert weighs in.
Is it safe to fly right now? An MIT professor calculated the risk of air travel during the pandemic in two different flight scenarios.
Designer antibodies could help treat and prevent COVID-19
A pair of new trials will test the ability of designer antibodies to not only treat COVID-19, but also potentially prevent coronavirus infections.
Updated coronavirus vaccine list: Where we stand today
A regularly updated coronavirus vaccine list highlighting the candidates closest to receiving approval from regulators.
Coronavirus treatment update: Where we stand today
Our latest coronavirus treatment update highlights the options that appear to work, ones that might, and ones that failed to live up to their promise.
Inhaled coronavirus drug shows promise in small trial
An inhaled coronavirus drug containing interferon beta decreased patients’ chances of becoming severely ill by 79%, according to its creator.
Remote therapy is as effective as face-to-face, for depression
The pandemic has therapists' couches off limits. A new study finds that remote therapy may be as effective for depression as face-to-face, so I gave it a try.
Oxford COVID-19 vaccine triggers strong immune response
An Oxford COVID-19 vaccine triggered the creation of antibodies and T cells in trial participants, according to promising results published in The Lancet.
How to explain falling COVID-19 mortality rates
COVID-19 mortality rates are dropping in the U.S. and other nations — a few theories explain why more people are surviving the coronavirus.
"T cells" could provide immunity after antibodies fade
T cells that combat SARS-CoV-2 have been discovered in people who never had COVID-19, potentially putting natural herd immunity within our grasp.
Moderna’s COVID-19 vaccine produces more antibodies than infection
Two shots of Moderna’s COVID-19 vaccine produces more antibodies than a coronavirus infection, according to Phase 1 preliminary data.
Study: Risk of death from COVID-19 is 45% lower on arthritis drug
The arthritis drug tocilizumab may lower ventilated patients' risk of death from COVID-19 by 45%, according to a retrospective study.
Survivors’ plasma might prevent coronavirus infections
Injections of COVID-19 survivors' blood plasma might prevent coronavirus infections, making them a promising stopgap until a vaccine is ready.
FDA: Smokeless cigarettes produce less harmful chemicals
FDA clears Philip Morris to market its smokeless cigarettes as modified risk tobacco products, which could benefit smokers battling a nicotine addiction.