Are near-death experiences just psychedelic trips?
One possible explanation of near death experiences is that our brains are flooded with a hallucinogenic, DMT.
Meth addiction treatments are finally on the horizon
New antibody and drug therapies may soon help treat meth patients, who currently have no pharmacological interventions.
San Francisco decriminalizes plant-based psychedelics
San Francisco joins Oakland, Santa Cruz, DC, and Denver in decriminalizing some psychedelics.
Microdosing’s benefits may be powered by belief
A small, double-blind, placebo-controlled study has found evidence that expectations may be behind microdosing’s beneficial effects.
The Biden administration is preparing for legal psychedelics within two years
The Biden administration’s Department of Health and Human Services has sent a memo supportive of psychedelic therapies. What does that mean for the field?
Your genes may impact psychedelic experiences
UNC researchers have found evidence that the genetic makeup of a crucial receptor may impact your psychedelic experience.
What your weed label really means
Through the largest analysis of commercial cannabis flower yet, Colorado researchers have found that the current labeling system falls short.
Archaeologists identify contents of ancient Mayan drug containers
Archaeologists used new methods to identify contents of Mayan drug containers, discovering a non-tobacco plant.
The first FDA-approved clinical trial of psilocin has begun
“This has never been done before,” says Filament’s CEO.
Psychedelic research returns to Veterans Affairs
After decades, the Department of Veterans Affairs is once again investigating psychedelic therapies.
A new delivery method for drugs that can’t withstand stomach acid
In order for a drug to get to the small intestine, it must first get past the highly acidic environment of the stomach.
Yale study of DMT for depression is encouraging
Yale researchers have conducted a small study finding DMT is safe and tolerable enough for more research.
Magic mushrooms evolved to scramble insect brains, send them on wild, scary trips
Researchers discovered that the way fungi independently gained the ability to produce psilocybin is because of horizontal gene transfer.
New drug combo is “a paradigm shift” in preventing asthma attacks
The combination of a rescue medication and a corticosteroid, taken as needed, reduced both short and long-term risk of asthma attacks.
How we treat inflammation may be causing chronic pain
Reversing common belief, researchers at McGill say treating inflammation may be causing chronic pain, not preventing it.
‘Mad honey’: The rare hallucinogen from the mountains of Nepal
On the mountainsides of Nepal and Turkey, bees sometimes produce a strange and dangerous concoction: mad honey.
AI maps psychedelic “trip” experiences to regions of the brain – opening new route to psychiatric treatments
To better understand how these effects manifest in the brain, we analyzed over 6,000 written testimonials of hallucinogenic experiences.
Closeup of a woman placing a pill in her mouth.
How the antidepressant Prozac could treat blindness
Prozac is a widely used antidepressant. Data indicates that the drug could be used to prevent blindness due to macular degeneration.
A close-up of a pipette
90% of drugs fail clinical trials – here’s one way researchers can select better drug candidates
It’s disappointing when the years of effort and resources spent to push a drug candidate to patients so often lead to failure.
A pile of empty prescription pill bottles.
Opioid overdose: A bioethicist explains why restricting supply may not be the right solution
Since the unpredictability of drug supply increases overdose risk, making the drug supply predictable should be part of the solution, right?
Atlantic horseshoe crab at St. Lucie County Marine Center in Fort Pierce, St. Lucie County, Florida, U.S.A.
Horseshoe crabs are drained for their blue blood. That practice will soon be over.
One of humanity’s strangest and most macabre activities is slowly coming to an end, a trend that every horseshoe crab should celebrate.
public health vending machines
Harm reduction vending machines are coming to New York
New York City has announced a pilot program installing public health vending machines with overdose drugs and clean needles.
Ketamine therapy may help former drinkers stay abstinent
A new study has found evidence that ketamine, combined with therapy, can help people with alcohol addiction abstain longer.
ergot alkaloids
Morning glories may be a source of new psychedelics and medicines
Researchers have found that the symbiotic relationship between a fungus and a morning glory holds the potential for new psychedelic compounds and medicines.
cannabis cooking
Traditional Thai cannabis cooking is back on the menu
Cannabis cooking has long simmered in Thailand. With the ruling junta’s new drug policies, the traditional dish is now making its way onto restaurant plates.
Should psychedelics be patented?
The issue of patents has riven the psychedelic field. A lawyer’s repository of psychedelic info may make sure the new field stays fair.
The DMT ‘elves’ people meet while tripping
Why do so many people encounter these 'elves' after smoking large doses of DMT?
Frontline healthcare workers are going to receive psilocybin therapy
University of Washington researchers are enrolling healthcare workers now in a psilocybin-assisted therapy study.
naloxone
This device can automatically detect and reverse opioid overdoses
Researchers at the University of Washington have developed an AI-powered wearable to detect, and reverse via naloxone injection, opioid overdoses.
Psychedelics can change how you think about the universe
A new study finds that a single trip on a psychedelic can cause lasting changes in a person's metaphysical beliefs.
Psilocybin treatment
Psilocybin treatment relieves depression in largest trial yet
The largest psilocybin treatment trial to date suggests that the psychedelic drug can help people with treatment-resistant depression.
harm reduction
Rhode Island will be the first state to open safe drug consumption sites
In an important test of drug harm reduction techniques, Rhode Island is set to become the first state to open safe consumption sites.
opioid vaccine
Trial of opioid vaccine launches in US
An opioid vaccine that prevents people with opioid use disorder from feeling “high” when they take oxycodone is moving to human trials.
dendritic spines
Yale study: magic mushrooms may grow connections between brain cells
A single dose of psilocybin caused increased growth in neuron-connecting dendritic spines in mice.
Is DMT the best new treatment for depression?
Psychedelic therapy could bring the ancient healing powers of drugs like DMT into mental health clinics.
gsk digital twin pharmaceutical factory
Pharma giant GSK embraces digital twins for vaccine development
Pharma leviathan GlaxoSmithKline is rolling out digital twins to help create “the vaccine factory of the future.”
nitrous oxide for depression
Low doses of nitrous oxide may treat depression
A new, small study has found that low doses of nitrous oxide — laughing gas — can treat symptoms of depression.
tbg for stress
A small dose of an ibogaine-like drug cures stress in mice
A novel drug designed like ibogaine but without the ibogaine trip or toxicity has corrected the effects of stress in mice.
ketamine infusion
Ketamine infusion: What it's like and how it works
Ketamine infusion therapy takes the anesthetic from dance floors to depression clinics. But how does the drug work, and what is it like?
MDMA for PTSD
MDMA for PTSD just crushed its phase 3 trial
Results from the first phase 3 trial of using MDMA for PTSD along with talk therapy found the drug to be effective.
psilocybin for depression
Phase 2 trial finds psychedelic works as well as common drug
A small study has provided evidence of psilocybin for depression working as well as a popular SSRI.
bad trip support line
Fireside Project is a support line for your bad trip
Fireside Project is a nonprofit that is providing a support line for your challenging psychedelic experiences — read: bad trip.
CBD for pain
"Complex" and "exciting": Researchers study the use of CBD for pain
In a small study, researchers at Syracuse found that both thinking you’re getting CBD for pain and the drug increase pain tolerance.
cannabis intoxication
How long are you too high to drive? The science is fuzzy.
Some drug driving laws outlaw any amount of THC. To create better laws, researchers are trying to find out how long cannabis intoxication itself lasts.
CBD and antibiotics
Can CBD be the next superbug slayer?
In the search for new weapons against superbugs, CBD and antibiotics in combination, as well as CBD alone, may prove to be promising candidates.
psychedelic medicine
NYU is launching a center for psychedelic medicine
NYU’s Center for Psychedelic Medicine will serve as the nexus for the school’s psychedelic research, as well as provide training to budding researchers.
MDMA for alcohol addiction
First-of-its-kind pilot study uses MDMA for alcohol addiction
A small, first-of-its-kind study has piloted the use of MDMA for alcohol addiction therapy.
oral ketamine treatment
Oral ketamine treatment reduced suicidal thoughts: Pilot study
A new, small study in Australia suggests that oral ketamine treatment may help treat suicidal thoughts.
effects of LSD
Friendly little mice are helping us understand the effects of LSD
Researchers at McGill have discovered the mechanisms behind the sociable effects of LSD in mice.
psychedelic research center
Mount Sinai is opening a psychedelic research center
A pacesetting institution, the Icahn School of Medicine at Mount Sinai is opening a psychedelic research center focusing on MDMA and trauma.
cannabis dosing smart vape pen
Smart vape pen claims to solve the cannabis dosing problem
To solve the cannabis dosing problem, the MODE smart vape vibrates when a person should stop inhaling and again when they should exhale.
ibogaine for addiction depression
Tweaked psychedelic drug could treat addiction, depression
A modified ibogaine molecule could be a safer and more accessible treatment for addiction and depression than the psychedelic drug in its natural state.
MDMA Couples Therapy
MDMA couples therapy could help couples dealing with PTSD
A small study out of Canada investigated the potential of using MDMA-assisted couples therapy to treat PTSD.
microdosing mushrooms
Microdosing mushrooms: Explained
Microdosing mushrooms — taking doses of psilocybin too small to cause a trip to enhance daily life — is gaining momentum. But does science support it?
cbd driving
CBD does not impair driving, study finds
A new study has demonstrated that CBD is safe for driving, while the effects of THC last only a few hours. This work could inform cannabis use laws.
Psilocybin Therapy
Psilocybin therapy appears to dramatically reduce depression
Psilocybin therapy — a combination of traditional therapy and supervised “trips” on the magic mushroom compound — shows promise as a depression treatment.
mdma therapy
MDMA therapy and the promise of psychedelics
Despite years of work with a "stellar" therapist, Charlotte needed more. She turned to MDMA therapy.
Scientists can induce out-of-body experiences without drugs
The human brain is a powerful and mysterious place, and researchers have just gotten closer to understanding another important phenomenon taking place inside dissociative experiences.
candy-flipping
“Candy flipping” — mixing MDMA and LSD — is hitting the lab
A clinical trial of mixing LSD and MDMA, known as “candy flipping,” wants to see if molly can take a trip’s edge off and make LSD therapy more effective.
microdosing lsd
Microdosing LSD may provide pain relief
Since the 1960s, LSD has been seen as a potential painkiller. Now, new research suggests microdosing LSD may indeed provide relief.
Psychedelic Mushrooms
Scientists want to study your at-home psychedelic mushroom experiences
Scientists are looking for people planning to trip on psychedelic mushrooms for a new study focused on people’s “real-world” experiences with psilocybin.
Psychedelic-Assisted Therapy
App brings psychedelic-assisted therapy into your home
The Field Trip app aims to help people get some of the benefits of psychedelic-assisted therapy outside the confines of a clinic.
ayahuasca experience
One ayahuasca experience could have lasting effects on the brain
Researchers believe just one ayahuasca experience may be enough to have a lasting effect on the brain.
Afghan Farmers Solar Panels Opium
Afghan farmers use solar panels to grow food — and opium
Farmers in Afghanistan are taking advantage of cheap solar panels to power the water pumps they use to irrigate crops for food and opium production.
Microdosing Marijuana
Microdosing marijuana can relieve chronic pain
Microdosing marijuana can relieve chronic pain without impairing a person’s ability to think clearly, according to a new study.
toad venom
Psychedelic toad venom explained
5-MeO-DMT, a psychedelic found in toad venom, causes mushroom-intense trips that are over quick. Could it have more accessible therapeutic potential?
PTSD Treatment
MDMA has long-lasting benefits as a PTSD treatment
The benefits of MDMA therapy as a PTSD treatment appear to last for at least a year, according to a newly published paper.
psilocybin
Psilocybin may impact your ego center
You’ve heard about “ego death” on magic mushrooms. New research suggests psilocybin curbs part of the brain that may tie in to ego.
New Antidepressants
Ketamine discovery may lead to new antidepressants
Researchers have uncovered new insights into how ketamine affects the brain, potentially illuminating the path to new antidepressants.
psilocybe cubensis beer yeast
This company is using beer yeast to make psilocybin
Brewing the magic in Psilocybe cubensis is difficult at scale. One Danish company thinks beer yeast may be the answer.
the war on drugs
Series | Dope Science
Are social media giants censoring life saving drug research?
The first casualty of war is truth, and that applies to the war on drugs. Some are fighting back with harm reduction and drug education, yet they’re facing opposition from an unexpected source.
new cancer treatment
CBD slows growth of brain cancer cells in a Petri dish
The cannabis compound CBD can slow the growth of brain cancer cells, but it’s a long way from a new cancer treatment.
LSD Trip
An LSD trip “off-switch” may be coming soon
Pharmaceutical startup MindMed is developing tech it believes could serve as an “off switch” for an LSD trip during therapy sessions.
ketamine and virtual reality
Could VR change how you trip on ketamine?
Virtual reality meets ketamine therapy to help treat pain, anxiety, and depression, to name a few.
interview with Brian D. Earp
The case for love-enhancing drugs
Drugs don’t just affect the user; they shape relationships too. And a pair of bioethicists thinks we should consider them for relationship enhancement.
safe injection sites
Safe injection sites are legal, US court rules
A U.S. judge has ruled that safe injection sites, places where users can consume drugs under medical supervision, don’t violate federal drug laws.
criminal record clearance
Algorithm clears thousands of marijuana convictions in just one minute
With this new system that identifies candidates for criminal record clearance and even auto-fills forms, offenders don’t even need to apply.
ketamine for depression
Series | Dope Science
I use ketamine for depression – here’s how it works
Commonly known as a party drug, ketamine’s powerful effects on the brain have led doctors to further explore its medical potential. Now, the animal anesthetic is providing relief and hope for people with severe depression.
Intro to LSD
LSD, also known as acid, is a synthetic chemical that causes hallucinations, synesthesia, and sometimes, distress - the dreaded “bad trip.”
MDMA effects
MDMA effects, risks, and rewards explained
MDMA, also known as Molly or Ecstasy, is a synthetic psychoactive drug. MDMA effects include enhanced pleasure and a heightened sense of touch and sound.
medical cannabis
Medical cannabis explained
Medical cannabis is everywhere. We're answering your basic questions and unpacking the promises and pitfalls, based on the latest research.
cannabis degree program
Legal pot is finally growing up and going to college
As medical marijuana becomes mainstream, so does the need for an educated workforce in the industry. Enter the nation's first-ever cannabis degree program.
ibogaine
Ibogaine: The psychedelic cure?
Ibogaine, an African psychedelic drug which comes from the iboga plant, is used for both religious rites and drug addiction treatment.
thc for endometriosis
THC could help women with endometriosis
Hundreds of thousands of women suffer with endometriosis, a disorder that causes painful tissue growth outside of the uterus. Pending clinical trials around THC may finally spell relief.
medicinal cannabis research
CRISPR may unlock targeted cannabis therapy
New medicinal cannabis research shows potential for personalized drug therapy, without the side effects.
drug use
Series | Dope Science
The Drug Users Bible: A guide to safe drug use
Over a 10 year period, Dominic Milton Trott self-administered 157 psychoactive drugs and documented his experiences on each one. He then created the book, The Drug Users Bible, to inform curious minds about safe drug use.
Psychedelic mushrooms explained
Psychedelic mushrooms, AKA magic mushrooms or psilocybin mushrooms, are currently being researched as a treatment for depression, addiction, and more.
microdosing psychedelics
Series | Dope Science
Microdosing psychedelics
Microdosing is the no-flowers-in-your-hair practice of regularly taking minimal amounts of hallucinogenic substances. Although it’s currently illegal, millions of dollars are being poured into further research.
special K drug ketamine
Ketamine explained: Understanding the special k drug
Ketamine, known recreationally as the “Special K” drug, is a trance-inducing anesthetic that researchers believe has more powerful uses off the dance floor.
mdma therapy for ptsd
Healing PTSD with MDMA therapy
New hope for PTSD sufferers is coming from an expected quarter: MDMA.
drug to curb meth addiction
We may have found a drug to curb meth addiction
Meth addiction is on the rise, so this team of researchers is working to develop the first FDA-approved medication to treat the use disorder.
studying psychedelics and depression
New promise for psychedelics and depression
New findings on psychedelics and depression show the benefits of microdosing, and could present more effective treatment options.
Natural Treatment for Autism
Series | Dope Science
Cannabis as a natural treatment for autism
When typical medications simply aren’t doing enough to manage their children’s symptoms, mothers like Jenni Mai are turning to medical marijuana. But with current regulations, parents are having to become pharmacists for their own families, and some are even moving across the country so they can legally access cannabis.
Removing the stigma of marijuana and autism
Marijuana and autism: Removing the stigma
Research is beginning to prove the hopeful connection between marijuana and autism treatment for symptom relief. Here is one man’s inspiring story.
Take a trip to Johns Hopkins' new psychedelic research center
Johns Hopkins is throwing its considerable clout behind the fast-growing field of psychedelic research, pouring $17 million into a research center to study the hallucinogenic drugs.
Scientists sidestep restrictions on cannabis research by taking their lab mobile
This mobile lab, run by scientists at the University of Colorado Boulder, is one of several workarounds developed...
Why drugs are hurting more people than ever – and what to do about it
Is the solution to dangerous drugs... making them safer?
How the Phoenix is fighting addiction with fitness
Meet the group that is helping thousands of people transform their lives and unlock their potential.
FDA approves the first marijuana-based drug
The drug has been proven effective at reducing seizures from certain types of childhood epilepsy.
Series | DIY Science
Can coding prevent overdoses?
A group of teenagers in Baltimore have created an app that can notify the public about heroin overdoses and save countless lives