Bad trips: Study examines the long-term adverse effects of psychedelic drugs
New research suggests that some users face long-term difficulties following psychedelic use, including emotional and social challenges.
The psychedelic DMT causes the brain to become hyperconnected, scans reveal
Researchers gave 20 healthy subjects potent, intravenous doses of the psychedelic DMT and observed their brains. Here's what they found.
“I’ve been here before”: DMT study explores a strange memory phenomenon
DMT can induce a sense of profound familiarity, making users feel as if they have entered an alternate reality they have visited before.
New clinical trial is testing a ketamine skin cream for PTSD
A topical ketamine treatment designed to alleviate the symptoms of PTSD without causing hallucinations has entered clinical trials.
New nasal spray aimed at reversing fentanyl overdoses is now approved
A new overdose-reversing spray that works fast but lasts longer has been approved by the FDA, and will be available by the fall at earliest.
Rapamycin: The unlucky history of the most powerful anti-aging drug
When rapamycin research was revived, it was found to have both anti-cancer and anti-aging properties. Here's what researchers say today.
Narcan is now available over-the-counter in the US
Naloxone administered by nasal spray can be a lifesaving drug with minimal side effects. It's now approved for over-the-counter use in the U.S.
Psychedelics open a new window on the mechanisms of perception
Some neuroscientists think psychedelics and the hallucinations they induce could help reveal how we generate our perceptions of the world.
New fentanyl vaccine could help avoid relapses and overdoses
An in-development fentanyl vaccine that prevents the drug from entering the brain could one day help people avoid relapsing or overdosing.
Biden pardons federal cannabis possession cases, urges states to do the same
The Biden administration is pardoning federal possession offenses, encouraging states to do the same, and reexamining its drug scheduling.
The Biden administration is preparing for legal psychedelics within two years
The Biden administration’s Department of Health and Human Services has sent a memo supportive of psychedelic therapies. What does that mean for the field?
Magic mushrooms evolved to scramble insect brains, send them on wild, scary trips
Researchers discovered that the way fungi independently gained the ability to produce psilocybin is because of horizontal gene transfer.
New drug combo is “a paradigm shift” in preventing asthma attacks
The combination of a rescue medication and a corticosteroid, taken as needed, reduced both short and long-term risk of asthma attacks.
AI maps psychedelic “trip” experiences to regions of the brain – opening new route to psychiatric treatments
To better understand how these effects manifest in the brain, we analyzed over 6,000 written testimonials of hallucinogenic experiences.
90% of drugs fail clinical trials – here’s one way researchers can select better drug candidates
It’s disappointing when the years of effort and resources spent to push a drug candidate to patients so often lead to failure.
Opioid overdose: A bioethicist explains why restricting supply may not be the right solution
Since the unpredictability of drug supply increases overdose risk, making the drug supply predictable should be part of the solution, right?
Horseshoe crabs are drained for their blue blood. That practice will soon be over.
One of humanity’s strangest and most macabre activities is slowly coming to an end, a trend that every horseshoe crab should celebrate.
Morning glories may be a source of new psychedelics and medicines
Researchers have found that the symbiotic relationship between a fungus and a morning glory holds the potential for new psychedelic compounds and medicines.
Traditional Thai cannabis cooking is back on the menu
Cannabis cooking has long simmered in Thailand. With the ruling junta’s new drug policies, the traditional dish is now making its way onto restaurant plates.
This device can automatically detect and reverse opioid overdoses
Researchers at the University of Washington have developed an AI-powered wearable to detect, and reverse via naloxone injection, opioid overdoses.
Psilocybin treatment relieves depression in largest trial yet
The largest psilocybin treatment trial to date suggests that the psychedelic drug can help people with treatment-resistant depression.
Rhode Island will be the first state to open safe drug consumption sites
In an important test of drug harm reduction techniques, Rhode Island is set to become the first state to open safe consumption sites.
"Complex" and "exciting": Researchers study the use of CBD for pain
In a small study, researchers at Syracuse found that both thinking you’re getting CBD for pain and the drug increase pain tolerance.
How long are you too high to drive? The science is fuzzy.
Some drug driving laws outlaw any amount of THC. To create better laws, researchers are trying to find out how long cannabis intoxication itself lasts.
NYU is launching a center for psychedelic medicine
NYU’s Center for Psychedelic Medicine will serve as the nexus for the school’s psychedelic research, as well as provide training to budding researchers.
Smart vape pen claims to solve the cannabis dosing problem
To solve the cannabis dosing problem, the MODE smart vape vibrates when a person should stop inhaling and again when they should exhale.
Tweaked psychedelic drug could treat addiction, depression
A modified ibogaine molecule could be a safer and more accessible treatment for addiction and depression than the psychedelic drug in its natural state.
Psilocybin therapy appears to dramatically reduce depression
Psilocybin therapy — a combination of traditional therapy and supervised “trips” on the magic mushroom compound — shows promise as a depression treatment.
Scientists can induce out-of-body experiences without drugs
The human brain is a powerful and mysterious place, and researchers have just gotten closer to understanding another important phenomenon taking place inside dissociative experiences.
“Candy flipping” — mixing MDMA and LSD — is hitting the lab
A clinical trial of mixing LSD and MDMA, known as “candy flipping,” wants to see if molly can take a trip’s edge off and make LSD therapy more effective.
Scientists want to study your at-home psychedelic mushroom experiences
Scientists are looking for people planning to trip on psychedelic mushrooms for a new study focused on people’s “real-world” experiences with psilocybin.
Afghan farmers use solar panels to grow food — and opium
Farmers in Afghanistan are taking advantage of cheap solar panels to power the water pumps they use to irrigate crops for food and opium production.
Series| Dope ScienceAre social media giants censoring life saving drug research?
The first casualty of war is truth, and that applies to the war on drugs. Some are fighting back with harm reduction and drug education, yet they’re facing opposition from an unexpected source.
Algorithm clears thousands of marijuana convictions in just one minute
With this new system that identifies candidates for criminal record clearance and even auto-fills forms, offenders don’t even need to apply.
Series| Dope ScienceI use ketamine for depression – here’s how it works
Commonly known as a party drug, ketamine’s powerful effects on the brain have led doctors to further explore its medical potential. Now, the animal anesthetic is providing relief and hope for people with severe depression.
Legal pot is finally growing up and going to college
As medical marijuana becomes mainstream, so does the need for an educated workforce in the industry. Enter the nation's first-ever cannabis degree program.